The Molecular Basis of Human Cancer

<div>Chapter 1</div><div>Cancer Epidemiology: Incidence and Etiology of Human Neoplasms</div><div>William B. Coleman and Gregory J. Tsongalis</div><div><br></div><div>Chapter 2</div><div>Essential Concepts and Techniques in Molecular Biology</div><div>Claudine L. Lefferts, PhD and Joel A. Lefferts, PhD</div><div><br></div><div>Chapter 3<div>Cancer Genomics</div><div>Jonathan R. Pollack</div><div><br></div><div>Chapter 4</div><div>Cancer Cytogenetics</div><div>Thomas Ried, Kerstin Heselmeyer-Haddad, Jordi Camps, and Timo Gaiser</div><div><br></div><div>Chapter 5</div><div>The Epigenetic Basis of Human Cancer</div><div>Thomas Mikeska and Alexander Dobrovic</div><div><br></div><div>Chapter 6</div><div>Cancer Proteomics</div><div>Jeffrey M. Lake and Timothy D. Veenstra</div><div><br></div><div>Chapter 7</div><div>An Overview of Cancer Genes</div><div>Ashley G. Rivenbark, PhD</div><div><br></div><div>Chapter 8</div><div>Oncogenes and the Initiation and Maintenance of Tumorigenesis</div>Dean W. Felsher, Constadina Arvanitis, Pavan Bendapudi, and Pavan Bachireddy</div><div><br></div><div>Chapter 9</div><div>Positive Mediators of Cell Proliferation in Neoplasia: Growth Factors and Receptors</div><div>Luca Grumolato, Ph.D. and Stuart Aaronson, M.D.</div><div><br></div><div>Chapter 10</div><div>Senescence, Apoptosis, and Cancer</div><div>Manjari Dimri and Goberdhan P. Dimri</div><div><br></div><div>Chapter 11</div><div>Novel Cancer Therapies Targeting Angiogenesis</div><div>Monte Willis and Nancy Klauber-DeMore</div><div><br></div><div>Chapter 12</div><div>Beyond the Primary Tumor: Progression, Invasion, and Metastasis</div><div>Danny R. Welch, Ph.D. and Douglas R. Hurst, Ph.D.</div><div><br></div><div>Chapter 13</div><div>Simple Sequence Mutations</div><div>Christophe Béroud and Mireille Claustres</div><div>Chapter 14</div><div>Single Nucleotide Polymorphisms and Cancer Susceptibility</div><div>Richard A. Hubner and Richard S. Houlston</div><div><br></div><div>Chapter 16Chromosomes and Chromosomal Instability in Human Cancer</div><div>Kazuma Ohyashiki, Masahiko Kuroda, and Junko H. Ohyashiki</div><div><br></div><div>Chapter 17</div><div>Epigenetic Mechanisms in Cancer Development</div><div>José Ignacio Martín-Subero and Manel Esteller</div><div><br></div><div>Chapter 18<div>MicroRNAs and Cancer</div><div>Phong Trang, Joanne Weidhaas, and Frank J. Slack</div><div><br></div><div>Chapter 19</div><div>Erionite and Asbestos in the Pathogenesis of Human Malignant Mesotheliomas</div><div>Mutlay Sayan and Brooke T. Mossman</div><div><br></div><div>Chapter 20</div><div>Viral Mechanisms in Human Carcinogenesis<div>Paul F. Lambert, PhD</div><div><br></div><div>Chapter 21</div><div>Hormonal Carcinogenesis: The Role of Estrogens</div><div>William A. Ricke, Karin Williams, Jalissa Wynder, Ganesh Palapattu, Yuzhuo Wang, Gerald R. Cunha</div><div><br></div><div>Chapter 22</div><div>Sporadic Cancers</div><div>Clemens B. Tempfer and Marc-André Reymond<div>&lt;<div>Chapter 23</div><div>Hereditary Cancer</div><div>Zoran Gatalica, MD, DSc, Anatole Ghazalpour, PhD Stan L. Lilleberg, PhD, Jeffrey Swensen, PhD, and Henry T. Lynch, MD</div><div><br></div><div>Chapter 24</div><div>Retinoblastoma: &nbsp;Clinical and Molecular Perspectives</div><div>Justis P. Ehlers MD and J. William Harbour MD</div><div><br></div><div>Chapter 25</div><div>Xeroderma Pigmentosum and the DNA Damage Response to Ultraviolet Light</div><div>James E. Cleaver</div><div><br></div><div>Chapter 26</div><div>Hereditary Colorectal Cancer</div><div>Sonia S. Kupfer and Nathan A. Ellis</div><div><br></div><div>Chapter 27</div><div>Lungs</div><div><hereditary breast="" and="" ovarian="" cancer<div>Michael P. Lux, Mayada R. Bani, Peter A. Fasching, and Matthias W. Beckmann</div><div><br></div><div>Chapter 28</div><div>The Molecular Basis of Prostate Carcinogenesis</div><div>Smitha Dutt and Allen C. Gao</div><div><br></div><div>Chapter 29</div><div>Molecular Basis of Lung Carcinogenesis</div>Kwun M. Fong, Jill E. Larsen, Casey Wright, Krishna Sriram, Morgan Davidson, Marissa Daniels, Yoshitaka Sekido, Rayleen V. Bowman, Ian A. Yang, and John D. Minna</div><div><br></div><div>Chapter 30</div><div>The Molecular Basis of Skin Carcinogenesis</div><div>Alessia Pacifico, MD, Giovanni Leone, MD, Honnavara N. Ananthaswamy, PhD</div><div><br></div><div>Chapter 31</div><div>The Molecular Biology of Leukemias</div><div>L. Jeffrey Medeiros and Sergej N. Konoplev</div><div><br></div><div>Chapter 32</div><div>Molecular Mechanisms in Non-Hodgkin Lymphoma</div><div>John Hunt, MD, Yuri Fedoriw, MD and William N. Rezuke, Jr., MD</div><div><br></div><div>Chapter 33</div><div>The Molecular Pathology of Head and Neck Squamous Cell Carcinoma</div><div>Laura J. Tafe</div><br></div><div>Chapter 34</div><div>Ovarian Cancer</div><div>Amy D. Brockmeyer and Louis Dubeau, MD, PhD</div><div><br></div><div>Chapter 35</div><div>Molecular Pathology of Bone and Soft Tissue Tumors</div><div>José Luis Ordóñez PhD, Daniel Osuna PhD, Juan Madoz-Gúrpide PhD, Enrique de Álava, MD, PhD</div><div><br></div><div>Chapter 36</div><div>The Molecular Biology of Human Brain Tumors</div><div>Daniel Coluccia, Adrienne Weeks, Javier Fandino, Christian Schneider, Christian Smith, and James T. Rutka</div><div><br></div><div>Chapter 37</div><div>Cancer Drug Discovery and Anticancer Drug Development</div><div>James Turkson, PhD</div><div><br></div><div>Chapter 38</div><div>Heart</div><div><biological principles="" and="" clinical="" application="" of="" egfr="" inhibitors="" in="" cancer<div>Zhuo (Georgia) Chen, PhD, Suresh Ramalingam, MD, and Dong M. Shin, MD</div><div><br></div><div>Chapter 39</div><div>Targeting Oncoproteins for Molecular Cancer Therapy</div><div>Joshua E. Allen and Wafik S. El-Deiry</div><div><br></div><div>Chapter 40</div><div>Therapeutic Agents that Inhibit Angiogenesis</div><div>Francesco Torino, Roberta Sarmiento, Raffaelle Longo, and Giampietro Gasparini</div><div><br></div><div>Chapter 41</div><div>Small Molecule Inhibitors</div><div>Xin Chen, Ph.D. and Jian Jin, Ph.D</div><div><br></div><div>Chapter 42</div><div>Molecular Detection and Diagnosis of Cancer</div><div>Christos Patriotis, Padma Maruvada, and Sudhir Srivastava</div><div><br></div><div>Chapter 43</div><div>Gene Therapy in the Treatment of Human Cancer</div><div>Anand C. Annan, MBBS, Paul B. Fisher, MPh, PhD, Paul Dent, PhD, Gene P. Siegal, MD, PhD, David T. Curiel, MD, PhD</div><div><br></div><div>Chapter 44</div><div>Personalized Medicine for the Treatment of Human Cancer</div><div>Scott A. Turner, PhD and Gregory J. Tsongalis, PhD</div><div><br></div></div></div></div>