Edward Kerns
- Auteur
Boeken van Edward Kerns
Li East Lyme, Ct
Li Di
Edward Institutes Of Health, Bethesda,
Edward Kerns
Edward Kerns
Drug-Like Properties
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials.
Meer
Ronald Borchardt
Edward Kerns
Christopher Lipinski
Dhrien Thakker
Binghe Wang
Pharmaceutical Profiling in Drug Discovery for Lead Selection
This volume focuses on how to increase the efficiency of drug discovery and development. It is written by experienced discovery scientists from diverse disciplines, including chemistry, drug metabolism, and development sciences.
Meer
Ronald Borchardt
Edward Kerns
Michael Hageman
Dhrien Thakker
James Stevens
Optimizing the "Drug-Like" Properties of Leads in Drug Discovery