Radical SAM Enzymes

<p>1. Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain<br>Gemma L. Holliday, Eyal Akiva, Elaine C. Meng, Shoshana D. Brown, Sara Calhoun, Ursula Pieper, Andrej Sali, Squire J. Booker and Patricia C. Babbitt<br>2. Purification and Characterization of the Choline Trimethylamine-Lyase (CutC)-Activating Protein CutD<br>Smaranda Bodea and Emily P. Balskus<br>3. QueE: A Radical SAM Enzyme Involved in the Biosynthesis of 7-Deazapurine Containing Natural Products<br>Julia K. Lewis, Nathan A. Bruender and Vahe Bandarian<br>4. TYW1: A Radical SAM Enzyme Involved in the Biosynthesis of Wybutosine Bases<br>Anthony P. Young and Vahe Bandarian<br>5. Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL)<br>Dhananjay M. Bhandari, Dmytro Fedoseyenko and Tadhg P. Begley<br>6. Aminofutalosine Synthase (MqnE): A New Catalytic Motif in Radical SAM Enzymology<br>Sumedh Joshi, Dmytro Fedoseyenko, Nilkamal Mahanta and Tadhg P. Begley<br>7. Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B<SUB>12</SUB>-Dependent Radical SAM Enzyme in Cystobactamid Biosynthesis<br>Yuanyou Wang, Bastien Schnell, Rolf Müller and Tadhg P. Begley<br>8. Biochemical Approaches for Understanding Iron-sulfur Cluster Regeneration in Escherichia coli Lipoyl Synthase during Catalysis<br>Erin L. McCarthy and Squire J. Booker<br>9. Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide<br>Bo Wang, Joseph W. LaMattina, Edward D. Badding, Lauren K. Gadsby, Tyler L. Grove and Squire J. Booker<br>10. Mechanistic Studies of Radical SAM Enzymes: Pyruvate Formate-Lyase Activating Enzyme and Lysine 2,3-Aminomutase Case Studies<br>Amanda S. Byer, Elizabeth C. McDaniel, Stella Impano, William E. Broderick and Joan B. Broderick<br>11. Determining Redox Potentials of the Iron–Sulfur Clusters of the AdoMet Radical Enzyme Superfamily<br>Stephanie J. Maiocco, Lindsey M. Walker and Sean J. Elliott<br>12. Radical S-Adenosyl-L-Methionine (SAM) Enzyme Involved in the Maturation of the Nitrogenase Cluster<br>Lee Rettberg, Kazuki Tanifuji, Andrew Jasniewski, Markus Walter Ribbe and Yilin Hu<br>13. Purification, Characterization, and Biochemical Assays of Biotin Synthase from Escherichia coli<br>Julia D. Cramer and Joseph T. Jarrett<br>14. Methods for Expression, Purification, and Characterization of PqqE, a Radical SAM Enzyme in the PQQ Biosynthetic Pathway<br>Wen Zhu, Ana M. Martins and Judith P. Klinman<br>15. Methods for Studying the Radical SAM Enzymes in Diphthamide Biosynthesis<br>Min Dong, Yugang Zhang and Hening Lin<br>16. Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products<br>Leah B. Bushin and Mohammad R. Seyedsayamdost<br>17. Identification of the Radical SAM Enzymes Involved in the Biosynthesis of Methanopterin and Coenzyme F<SUB>420</SUB> in Methanogens<br>Kylie D. Allen and Robert H. White<br>18. Lessons From the Studies of a C-C Bond Forming Radical SAM Enzyme in Molybdenum Cofactor Biosynthesis<br>Haoran Pang and Kenichi Yokoyama</p>