Stephen H. Tsang
CRISPR Genome Surgery in Stem Cells and Disease Tissues
Paperback Engels 2021 9780128178768Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature.
Specificaties
Lezersrecensies
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Inhoudsopgave
1. History of CRISPR
2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.)
3. Genome engineering in iPSC cells
4. CRISPR manipulations in stem cell lines for neurological diseases
5. Gene editing for the cornea
6. CRISPR screening for eye diseases
7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration
8. Ethics of Gene Editing in Human Stem Cells
9. sGRNA
10. CRISPR vs ZFN/TALEN
2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.)
3. Genome engineering in iPSC cells
4. CRISPR manipulations in stem cell lines for neurological diseases
5. Gene editing for the cornea
6. CRISPR screening for eye diseases
7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration
8. Ethics of Gene Editing in Human Stem Cells
9. sGRNA
10. CRISPR vs ZFN/TALEN
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