John T. Schmidt
Self-organizing Neural Maps: The Retinotectal Map and Mechanisms of Neural Development
From Retina to Tectum
Paperback Engels 2019 9780128185797Levertijd ± 9 werkdagen
Gratis verzonden
Samenvatting
Self-organizing Neural Maps: From Retina to Tectum describes the underlying processes that determine how retinal fibers self-organize into an orderly visual map. The formation of neural maps is a fundamental organizing concept in neurodevelopment that can shed light on developmental mechanisms and the functions of genes elsewhere. The book presents a summary of research in the retinotectal field with an ultimate goal of synthesizing how underlying mechanisms in neural development harmoniously come together to create life. A broad spectrum of neuroscientists and biomedical scientists with differing backgrounds and varied expertise will find this book useful.
Specificaties
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Inhoudsopgave
1. Overview and Basics of the Retinotectal Projection2. Early Work Supports, but Also Contradicts, Rigid Chemoaffinity3. The search for chemoaffinity molecules - verification of molecular gradients4. Plasticity after surgical ablations shows the limits of chemoaffinity5. Natural Plasticity - Analysis of the effects of divergent retinal and tectal growth on the projection6. Specification and developmental genetics of Eph/ephrin gradients7. Growth of retinal axons along the visual pathway8. Genetic Analysis of the molecular gradients defining map formation9. Activity mechanisms shape central retinal projections10. Activity: Molecular signaling to growth mechanisms
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