Richard A Ward,
Neil Grimster
The Design of Covalent-Based Inhibitors
Gebonden Engels 2021 9780128216897Levertijd ± 9 werkdagen
Gratis verzonden
Samenvatting
Annual Report on Medicinal Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Specificaties
Lezersrecensies
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Inhoudsopgave
Preface
Richard Andrew Ward and Neil Grimster
1. The history of covalent inhibitors
Renato A. Bauer
2. Kinetic Mechanisms of Covalent Inhibition
Claire Louise McWhirter
3. Covalent Drugs in Development for Immune-Mediated Diseases
Leonard Sung
4. Chemistry Perspectives of Reversible Covalent Drugs
Jianmin Gao
5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond Cysteine
Lyn Jones
6. Boron and Covalent Inhibition
Andrew Leach
7. Measuring and predicting warhead and residue reactivity
Christopher Rowley
8. Computational Support of Structure-based Targeted Covalent Inhibitor Design
Robert Abel
9. Novel approaches to covalent inhibition
Nir London
10. The future of covalent inhibition
Gyorgy M. Keseru
Richard Andrew Ward and Neil Grimster
1. The history of covalent inhibitors
Renato A. Bauer
2. Kinetic Mechanisms of Covalent Inhibition
Claire Louise McWhirter
3. Covalent Drugs in Development for Immune-Mediated Diseases
Leonard Sung
4. Chemistry Perspectives of Reversible Covalent Drugs
Jianmin Gao
5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond Cysteine
Lyn Jones
6. Boron and Covalent Inhibition
Andrew Leach
7. Measuring and predicting warhead and residue reactivity
Christopher Rowley
8. Computational Support of Structure-based Targeted Covalent Inhibitor Design
Robert Abel
9. Novel approaches to covalent inhibition
Nir London
10. The future of covalent inhibition
Gyorgy M. Keseru
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