Hui Kimko,
Stephen B. Duffull
Simulation for Designing Clinical Trials
A Pharmacokinetic-Pharmacodynamic Modeling Perspective
Paperback Engels 2019 9780367395605Levertijd ± 8 werkdagen
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Samenvatting
Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.
Specificaties
ISBN13:9780367395605
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:424
Uitgever:Taylor & Francis Ltd
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Inhoudsopgave
Introduction to Simulation for Design of Clinical Trials. Models for Simulation. Computation in Simulation. Analyses of the Simulations. Perspectives on Clinical Trial Simulation. Applications. Index.
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