Synthetic Peptide Vaccine Models

Design, Synthesis, Purification and Characterization

Paperback Engels 2022 9780367700881
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A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

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Inhoudsopgave

Chapter 1. Background

Chapter 2. Introduction to Vaccination

Chapter 3. Fundamentals of Modern Peptide Synthesis

Chapter 4. Peptide Synthesis and Characterization Stages

Chapter 5. Conjugation of Polymers with Biomolecules and Polymeric Vaccine Development Technologies

Chapter 6. What are Polymeric Carriers?

Chapter 7. Conjugation and Other Methods in Polymeric Vaccines

Chapter 8. Polymeric Nanoparticle Preparation Methods

Chapter 9. Peptides in Brain Disorders

Chapter 10. Pseudo-proteins and related synthetic amino acid based polymers promising for constructing artificial vaccines

Chapter 11. Peptide Vaccines in Cancer Diseases

Chapter 12. Antioxidant Peptides

Chapter 13. Peptide Vaccine

Chapter 14. Adjuvants Of Vaccine in Immunotoxicology

Chapter 15. Role of Epigenetics in Immunity and Immune Response to Vaccination

Chapter 16. "Omics" technologies in vaccine research

Chapter 17. Computer-Aided Epitope Identification and Design of Epitope Mimetics.

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          Synthetic Peptide Vaccine Models