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Cholecystokinin

From Gallbladder to Cognition and Beyond

Paperback Engels 2025 9780443237201
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.

Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.

Specificaties

ISBN13:9780443237201
Taal:Engels
Bindwijze:Paperback

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Inhoudsopgave

<p>Part I - History<br>1. Milestones in the history of cholecystokinin<br>Jens F. Rehfeld, Christine Feinle-Bisset<br> <br>Part II - Biology of cholecystokinin<br>2. Evolutionarily conserved roles of cholecystokinin signaling<br>Dick Nässel, Shunfan Wu<br> <br>3. The biogenesis and cell-specific expression of cholecystokinin peptides<br>Jens F. Rehfeld, Christine Feinle-Bisset<br> <br>4. Cholecystokinin in intestinal and extraintestinal endocrine cells<br>Marta Santoz Hernandez, Frank Reimann, Fiona M. Gribble<br> <br>5. Cholecystokinin in the central and peripheral nervous system<br>Tomas Hökfelt, Swapnali Barde, Wen Zhong, Jufang He<br> <br>6. Cholecystokinin 1 and cholecystokinin 2 receptors<br>Laurence J Miller<br> <br>7. The relationship between cholecystokinin and gastrin<br>Jens F. Rehfeld<br> <br>Part III - Physiology of cholecystokinin<br>8. Intestinal cholecystokinin secretion<br>Rashmi Chandra, Rodger A. Liddle<br> <br>9. Cholecystokinin and the gut-brain axis<br>Kirsteen Browning, Amanda Page<br> </p><br><ol><li>Cholecystokinin and the gallbladder</li></ol><br><p>Adrian A. M. Masclee, Gwen M. C. Masclee<br> <br>11. Cholecystokinin and the exocrine pancreas<br>John A. Williams<br> <br>12. Islet effects of cholecystokinin and exploitation in diabetes<br>Neil Tanday, Nigel Irwin, Peter Flatt<br> <br>13. Cholecystokinin and gastrointestinal motor function<br>Javad Anjom Shoae, Michael Horowitz, Christine Feinle-Bisset<br> <br>14. Effect of cholecystokinin on food intake and appetite<br>Frank A. Duca<br> <br>15. Cholecystokinin, nutrient preference and taste aversion<br>Jo E. Lewis, Fiona M. Gribble, Frank Reimann<br> <br>16. Cholecystokinin in peripheral and central cardiovascular control<br>Tony J. M. Verberne, Bashair M. Mussa<br> <br>17. Cholecystokinin in cardiac myocytes<br>Jens P. Goetze, Jens F. Rehfeld<br> <br>Part IV – Methods used for cholecystokinin research<br>18. Measurement of cholecystokinin in biological fluids<br>Jens F. Rehfeld, Jens P. Goetze<br> <br>19. Cholecystokinin knockout mice: peripheral and central phenotypes<br>Chunmin C. Lo, Dennis D. Black, Patrick Tso<br> <br>Part V - cholecystokinin in disease<br>20. Cholecystokinin in obesity and other disorders of eating<br>Kimberly R. Smith, Tim H. Moran<br> <br>21. Cholecystokinin in tumors<br>Jens F. Rehfeld<br> <br>22. Cholecystokinin and panic disorder<br>Jacques Bradwejn, Diana Koszycki<br> <br>23. Cholecystokinin and the immune system<br>John J. Worthington<br> <br>24. Cholecystokinin in nociception and pain<br>Nesia A. Zurek, Sascha R. A. Alles<br> <br>Part VI – cholecystokinin -based novel therapeutic approaches<br>25. Potential therapeutics targeting cholecystokinin 1 receptors<br>Laurence J. Miller<br> <br>Part VII - Conclusion<br>26. Reflections on cholecystokinin research: past, present and future<br>Jens F. Rehfeld, Christine Feinle-Bisset<br> </p>

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