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Protein Dynamics

Experimental and Computational Approaches

Paperback Engels 2026 9780443300424
€ 196,59
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Samenvatting

Protein Dynamics: Experimental and Computational Approaches investigates protein biology from a biophysical standpoint. The book covers a wide range of topics, including functional protein dynamics, intrinsically disordered proteins, protein folding, misfolding and aggregation, and membrane protein-protein communication. Protein allosteric conformational changes caused by drug binding and disease-associated mutations are also featured, alongside protein dynamics in the context of computer-based drug design. Biophysical techniques for investigating protein structure-dynamics-function relationships across these topics are explored, considering the latest experimental and computational approaches in the field. This book is an ideal reference for researchers in working in biophysics, biochemistry, and related areas.

Specificaties

ISBN13:9780443300424
Taal:Engels
Bindwijze:Paperback
Herdrukdatum:1-9-2026

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Inhoudsopgave

1. Introduction<br>2. Functional protein dynamics<br>3. Protein-protein communication in membrane protein organization and cell signaling<br>4. Intrinsically disordered proteins<br>5. Role of entropy in protein folding<br>6. Functional water molecules and role of ions in protein function<br>7. Computing transition states in enzyme reactions<br>8. G Protein Receptor Signaling<br>9. Protonation-coupled protein dynamics studied with graph algorithms<br>10. Membrane transporters<br>11. Lipids and lipid-protein dynamics in membrane protein function<br>12. Protein misfolding and aggregation<br>13. Proteins of extremophiles<br>14. Protein allosteric conformational changes caused by drug binding and disease-associated mutations<br>15. Computer-based drug design<br>16. Amyloid precursor protein in Alzheimer’s disease

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€ 196,59
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        Protein Dynamics