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Cellular Senescence and Cardiac Aging

Mechanisms, Therapeutic Strategies, and Implications for Cardiovascular Diseases

Paperback Engels 2026 9780443458118
€ 207,39
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Cellular Senescence and Cardiac Aging: Mechanisms, Therapeutic Strategies, and Implications for Cardiovascular Diseases offers a comprehensive and up-to-date exploration of the molecular and cellular processes driving cardiac aging, with a special focus on cellular senescence. This authoritative volume bridges cutting-edge, basic science with clinical applications, detailing how senescent cells contribute to age-related cardiovascular diseases and highlighting innovative therapeutic approaches such as senolytics and regenerative medicine. Ideal for graduate students, researchers, and clinicians in biomedical sciences, cardiology, pharmacology, and regenerative medicine, this book provides essential insights into biomarkers, epigenetics, autophagy, and emerging treatments.

With contributions from global experts, it also addresses gender and ethnic disparities, ensuring a broad and inclusive perspective. This indispensable resource equips readers with the knowledge needed to advance research and improve patient care in the rapidly evolving field of cardiac aging.

Specificaties

ISBN13:9780443458118
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:344

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Inhoudsopgave

  1. Introduction to cardiac aging and cellular senescence
  2. Cardiac aging beyond senescence: structural, functional, and physiological changes
  3. Molecular mechanisms of senescence in cardiomyocytes
  4. Cellular senescence in atherosclerosis and heart failure: pathophysiology and clinical implications
  5. Senescence-associated secretory phenotype in cardiac tissue
  6. Mitochondrial dysfunction, oxidative stress, and cardiac aging
  7. Telomere attrition and cardiovascular senescence
  8. Epigenetic modifications in cardiac aging and senescence
  9. Senescence-induced cardiac fibrosis and remodeling
  10. Metabolic disorders, obesity, and accelerated cardiac senescence
  11. Autophagy, mitophagy, and senescence in the heart
  12. Senolytics and senomorphics: emerging therapeutic strategies
  13. Biomarkers of senescence in cardiovascular diseases
  14. Noninvasive techniques for tracking cardiac aging
  15. Clinical trials and translational advances targeting cardiac aging

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€ 207,39
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          Cellular Senescence and Cardiac Aging