Bioconjugation Methods

Site-specific chemical conjugation of recombinant proteins onto the AAV capsid.- Bioorthogonal Surface Modification of Measles and Vaccinia Viruses Using Metabolic Azide Reporters.- Synthesis of linkage-specific polyubiquitin probes using unnatural amino acids.- Synthesis of Ub-ACA, a Fluorogenic DUB Substrate via ACPL Method.- Native Chemical Ligation to Install Chemical Protein Modifications.- Efficient and Site-Specific Protein Bioconjugation Quantification in Mammalian Cells.- Intelligence disclosure on deploying SpyTag/SpyCatcher for Nanoparticle Assembly.- Rapid and Wash-free Live Cell Labeling with BenzoTag.- Antibody Conjugation to Cell Surface Receptors.- Cysteine Re-bridging Using Divinyl Pyrimidine Reagents for the Generation of Antibody-Drug Conjugates.- Sortase A Catalyzed Transpeptidation for Protein Bio-engineering.- Attachment of 2-Pyridyltetrazine Affinity Bioorthogonal Chemistry (ABC) Tags to Proteins for Site-selective Bioorthogonal Chemistry.- N-acyl-N-alkyl sulfonamide mediated bioconjugation of His-tag fused proteins.- Chemoselective Histidine Bioconjugation Using Thiophosphorodichloridate Reagents.- Reactive DNA Probes for Cross-Linking with Specific Amino Acids of Protein.- Protein Modification via Bioorthogonal HS-BCN Ligation.