Giovanni Floris,
Rodolfo Federico,
Bruno Mondovi,
F. Boomsma,
Alessandra Cona,
Giuseppe Zanotti,
Hubert G. Schwelberger,
Alessandro Finazzi-Agro,
A. van den Meiracker
e.a.
Copper Amine Oxidases
Structures, Catalytic Mechanisms and Role in Pathophysiology
Gebonden Engels 2009 1e druk 9781420076806Levertijd ongeveer 11 werkdagen
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Samenvatting
Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities. This book describes the structure of the enzymes, the role of copper, and of the unusual cofactor 6-hydroxydopa quinine derived from a posttranslational modification of a tyrosine residue. It also covers the differences of between AOs from bacteria, plants, and mammals. Finally, the text examines the importance of this ubiquitous class of enzymes in physiology and in metabolism of biogenic amines.
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