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Cardiovascular Alterations in Metabolic Diseases

Gebonden Engels 2026 9783032321398
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Metabolic disorders such as obesity and diabetes are rapidly increasing worldwide and are major contributors to cardiovascular disease, including hypertension, vascular dysfunction, and diabetic cardiomyopathy. As the global burden of cardiometabolic disease continues to rise, understanding the molecular and cellular mechanisms linking metabolic dysfunction to cardiovascular injury has become increasingly important for the development of effective therapies. This volume provides a comprehensive overview of the mechanisms underlying cardiovascular dysfunction in metabolic disorders, integrating fundamental biology with translational and therapeutic perspectives. Bringing together contributions from leading investigators in the field, this book serves as a valuable resource for researchers, clinicians, and graduate students interested in cardiovascular physiology, metabolic disease, and translational medicine.

Specificaties

ISBN13:9783032321398
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:238
Uitgever:Springer Nature Switzerland

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Inhoudsopgave

Experimental Models for Studying Cardiovascular Dysfunction in Metabolic Syndrome.- Sexual Dimorphism in the Development of Cardiometabolic Syndrome.- Cardiac Cell Remodeling in Obesity and Diabetes.- Calcium Signaling Dysregulation in Diabetic Cardiomyopathy Roles of STIM and Orai Channels.- The SERCA Pump A Key Molecular Target in Calcium Handling of Vascular Smooth Muscle Cells in Metabolic Syndrome.- Oxidative Modifications in Cardiac Mitochondrial and Ca2+ Handling Proteins in Obesity and Metabolic Syndrome Antioxidant Alternatives.- Role of Innate Immune Receptors in Cardiac Damage Linked to Metabolic Disorders.- Cardiovascular Dysfunction in Type 2 Diabetes The Role of MicroRNAs.- In Search of a Biomarker for Vasculopathy Associated with Metabolic Syndrome.- Physical Activity and Its Impact on Cardiometabolic Disorders.

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          Cardiovascular Alterations in Metabolic Diseases