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Protein-Protein Interactions as New Drug Targets

Gebonden Engels 2008 2008e druk 9783540728429
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Samenvatting

Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.

This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

Specificaties

ISBN13:9783540728429
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:512
Uitgever:Springer Berlin Heidelberg
Druk:2008

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          Protein-Protein Interactions as New Drug Targets