Proteases and Their Inhibitors in Cancer Metastasis

1. Molecular Biology of the Plasminogen System: The delicate balance between tissue healing and tissue destruction; A. Luttun, P. Carmeliet. 2. Role of Serine Proteases and Their Inhibitors in Tumor Growth and Angiogenesis; A. Noël, J.-M. Foidart. 3. The Gelatinases, MMP-2 and MMP-9-Implications for Invasion and Metastasis; R.J. Muschel, Jiang Yong. 4. The Collagenases: Novel roles for matrix metallo-proteinases (MMPs) in invasion and metastasis; C.E. Brinckerhoff, U. Benbow, G.B. Tower. 5. Stromelysin-3, a Particular Member of the Matrix Metalloproteinase Family; M.-C. Rio. 6. Membrane-type Matrix Metalloproteinases; Y. Itoh, M. Seiki. 7. 3D Structure and Drug Design; J. Schröder, H. Wenzel, H. Tschesche. 8. Transcriptional Control of Proteases; H. Allgayer, E. Lengyel, D.D. Boyd. 9. Tissue Inhibitors of Metalloproteinases in Cancer; Y.A. DeClerck. 10. Clinical Aspects of Matrix Metalloproteinases; B. Nawrocki-Raby, C. Clavel, M. Polette, P. Birembaut. 11. Tissue Models to Study Tumor-Stroma Interactions; N.E. Fusenig, M. Skobe, S. Vosseler, M. Hansen. W. Lederle, K. Airola, P. Tomakidi, H.-J. Stark, H. Steinbauer, N. Mirancea, P. Boukamp, D. Breitkreutz. 12. Mammalian Heparanase; Molecular Properties Inhibition and Involvement in Tumor Metastasis and Angiogenesis; I. Vlodavsky, Y. Friedman, M. Elkin, O. Pappo, I. Pecker, M.D. Hulett, C.R. Parish, C. Freeman. Index.