Understanding DNA
The Molecule and How it Works
Gebonden Engels 2004 9780121550899Samenvatting
The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth.
The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.
Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.
Specificaties
Lezersrecensies
Inhoudsopgave
Why a Helix?
Different Kinds of Double Helix
Twisting and Curving
Curving in Three Dimensions
DNA Supercoiling
The Assembly of DNA intor Chromosomes
Specific DNA-Protein Interactions
Methods Used to Study the Structure of DNA
DNA in Disease, Diagnostics and Medicine
Cytosine Methylation and DNA Epigenetics
Appendix
1: Notes on the Derivation of Some Technical Terms
2: The Chemical Theory of Base-stacking Interactions in DNA
3: How to modify Gene Expression by means of Anti-sense Oligonucleotides, Ribozymes or si-RNA
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