Measuring Biological Responses with Automated Microscopy

<p>[1]: Dynamic Green Fluorescent Protein Sensors for High-Content Analysis of the Cell Cycle</p> <p>[2]: High-Content Fluorescence-Based Screening for Epigenetic Modulators</p> <p>[3]: Development of Assays for Nuclear Receptor Modulators Using Fluorescently Tagged Proteins</p> <p>[4]: The Ligand-Independent Translocation Assay: An Enabling Technology for Screening Orphan G Protein-Coupled Receptors by Arrestin Recruitment</p> <p>[5]: High-Content Screening of Known G Protein-Coupled Receptors by Arrestin Translocation</p> <p>[6]: Cell Imaging Assays for G Protein-Coupled Receptor Internalization: Application to High-Throughput Screening</p> <p>[7]: High-Throughput Confocal Microscopy for β-Arrestin–Green Fluorescent Protein Translocation G Protein-Coupled Receptor Assays Using the Evotec Opera</p> <p>[8]: G Protein-Coupled Receptor Internalization Assays in the High-Content Screening Format</p> <p>[9]: Screening for Activators of the Wingless Type/Frizzled Pathway by Automated Fluorescent Microscopy</p> <p>[10]: A Live Cell, Image-Based Approach to Understanding the Enzymology and Pharmacology of 2-Bromopalmitate and Palmitoylation</p> <p>[11]: High-Resolution, High-Throughput Microscopy Analyses of Nuclear Receptor and Coregulator Function</p> <p>[12]: Tracking Individual Proteins in Living Cells Using Single Quantum Dot Imaging</p> <p>[13]: Development and Application of Automatic High-Resolution Light Microscopy for Cell-Based Screens</p> <p>[14]: Adenoviral Sensors for High-Content Cellular Analysis</p> <p>[15]: Cell-Based Assays Using Primary Endothelial Cells to Study Multiple Steps in Inflammation</p> <p>[16]: Development and Implementation of Multiplexed Cell-Based Imaging Assays</p> <p>[17]: High-Throughput Screening for Modulators of Stem Cell Differentiation</p> <p>[18]: High-Content Kinetic Calcium Imaging in Drug-Sensitive and Drug-Resistant Human Breast Cancer Cells</p> <p>[19]: Measurement and Analysis of Calcium Signaling in Heterogeneous Cell Cultures</p> <p>[20]: Multiplex Analysis of Inflammatory Signaling Pathways Using a High-Content Imaging System</p> <p>[21]: Generation and Characterization of a Stable MK2-EGFP Cell Line and Subsequent Development of a High-Content Imaging Assay on the Cellomics ArrayScan Platform to Screen for p38 Mitogen-Activated Protein Kinase Inhibitors</p> <p>[22]: Development and Implementation of Three Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway Imaging Assays to Provide MAPK Module Selectivity Profiling for Kinase Inhibitors: MK2-EGFP Translocation, c-Jun, and ERK Activation</p> <p>[23]: Assay Development and Case History of a 32K-Biased Library High-Content MK2-EGFP Translocation Screen to Identify p38 Mitogen-Activated Protein Kinase Inhibitors on the ArrayScan 3.1 Imaging Platform</p> <p>[24]: Compound Classification Using Image-Based Cellular Phenotypes</p> <p>[25]: High-Content Screening: Emerging Hardware and Software Technologies</p> <p>[26]: An Infrastructure for High-Throughput Microscopy: Instrumentation, Informatics, and Integration</p> <p>[27]: Protein Translocation Assays: Key Tools for Accessing New Biological Information with High-Throughput Microscopy</p> <p>[28]: High-Content Screening of Functional Genomic Libraries</p> <p>[29]: Fluorescent Protein-Based Cellular Assays Analyzed by Laser-Scanning Microplate Cytometry in 1536-Well Plate Format</p> <p>[30]: High-Throughput Measurements of Biochemical Responses Using the Plate::Vision Multimode 96 Minilens Array Reader</p> <p>[31]: Systems Cell Biology Based on High-Content Screening</p> <p>[32]: Digital Autofocus Methods for Automated Microscopy</p> <p>[33]: Fluorescence Lifetime Imaging Microscopy: Two-Dimensional Distribution Measurement of Fluorescence Lifetime</p> <p>Author Index</p> <p>Subject Index</p>