David A. Cheresh
Integrins
Gebonden Engels 2007 9780123739247
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.
Specificaties
ISBN13:9780123739247
Taal:Engels
Bindwijze:Gebonden
Uitgever:Elsevier Science
Serie:Methods in Enzymology
Lezersrecensies
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Inhoudsopgave
Chapter 1: Quantitative Measurements of Integrin-Mediated Adhesion to Extracellular Matrix<br><br>Chapter 2: Investigating Integrin regulation and signaling events in three dimensional systems<br><br>Chapter 3: Integrins in Cell Migration<br><br>Chapter 4: Imtegrin Cytoskeletal Interacions<br><br>Chapter 5: Cell Survival in a 3D Matrix<br><br>Chapter 6: Platelet Integrin Adhesive Functions and Signaling<br><br>Chapter 7: Development of Monoclonal Antibodies to Integrin Receptors<br><br>Chapter 8: Cell adhesion, cellular tension, and cell cycle control<br><br>Chapter 9: Analysis of Integrin Signaling by Fluorescence Resonance Energy Transfer<br><br>Chapter 10: Studies on integrins in the nervous system<br><br>Chapter 11: Methods for identifying novel integrin ligands<br><br>Chapter 12: Analysis of integrin functions in peri-implantation embryos, hematopoietic system and skin<br><br>Chapter 13: Identification and molecular characterization of multiple phenotypes in integrin knockout mice<br><br>Chapter 14: Purification, Analysis and Crystal Structure of Integrins<br><br>Chapter 15: Electron Microscopy of Integrins<br><br>Chapter 16: Intravital Imaging and Cell Invasion<br><br>Chapter 17: Using Xenopus Embryos to Investigate Integrin Function<br><br>Chapter 18: Methods to Study Lymphatic Vessel Integrins<br><br>Chapter 19: Analysis of Integrin Signaling in Genetically Engineered Mouse Models of Mammary Tumor Progression<br><br>Chapter 20: Design and Chemical Synthesis of Integrin Ligands
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