Ya-Xiong Tao
G Protein-Coupled Receptors in Health and Disease, Part B
Gebonden Engels 2010 9780123747563
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field.
Specificaties
Lezersrecensies
Wees de eerste die een lezersrecensie schrijft!
Inhoudsopgave
1. Diseased G protein-coupled receptors: An Introduction<br>Ya-Xiong Tao<br>2. GPR56 and its related diseases<br>Xianhua Piao and Ze Tian<br>3. GnRHR mutations and hypogonadotropic hypogonadism<br>Nicholas de Roux <br>4. LHR mutations and reproductive disorders<br>Deborah L. Segaloff<br>5. FSHR mutations and reproductive disorders<br>Ya-Xiong Tao and Deborah L. Segaloff<br>6. V2R mutations and nephrogenic diabetes insipidus<br>Daniel G. Bichet <br>7. Calcium-sensing receptor mutations <br>Geoffrey N. Hendy <br>8. Diseases caused by prostacyclin receptor mutations<br>John Hwa and Kathleen A Martin
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