Development of T Cell Immunity

Gebonden Engels 2010 9780123812841
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Samenvatting

T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.

This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.

Specificaties

ISBN13:9780123812841
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:342

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Inhoudsopgave

Development of T cell immunity
  1. The development of T cell immunity – Adrian Liston
  2. The evolution of T cell immunity
  3. Genome duplication and T cell immunity – Masanori Kasahara
  • Questions arising from "Genome duplication and T cell immunity" – Claude Perreault
  • Response to questions – Masanori Kasahara
  1. The origin and role of MHC class I-associated self peptides – Claude Perreault
  • Questions arising from "The origin and role of MHC class I-associated self peptides" – Masanori Kasahara
  • Response to questions – Claude Perreault


Thymic requirements for T cell immunity
  1. Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation – Nancy Manley and Brian Condie
  2. Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia – Cedric S Tremblay, Thu Hoang and Trang Hoang
  3. T cell immunity in the periphery
  4. Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses – Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson
  • Commentary on "Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses" – Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
  1. Cellular and Molecular Requirements in Lymph Node and Peyer’s Patch Development – Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
  2. T follicular helper cells during Immunity and Tolerance – Michelle A. Linterman and Carola G. Vinuesa
  3. Preventing T cell-dependent autoimmunity
  4. Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells – Paola Romagnoli and Joost P.M. van Meerwijk
  5. Molecular Mechanisms of Regulatory T cell Development and Suppressive Function – Jeong M. Kim
    • Is Foxp3 the master regulator of regulatory T cells? – Adrian Liston

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          Development of T Cell Immunity