Muscle 2-Volume Set

<p>Part 1: Introduction</p> <p>1. An Introduction to Muscle</p> <p>2. A History of Muscle</p> <p>Part II: Cardiac Muscle</p> <p>Section A: Basic Physiology</p> <p>3. Cardiac Myocyte Specification and Differentiation</p> <p>4. Transcriptional Control of Cardiogenesis</p> <p>5. Cardiomyocyte Ultrastructure</p> <p>6. Overview of CArdiac Muscle Physiology</p> <p>7. Ionic Fluxes and Genesis of the Cardiac Action Potential</p> <p>8. G-Protein-Coupled Receptors in the Heart</p> <p>9. Receptor Tyrosine Kinases in Cardiac Muscle</p> <p>10. Communication in the Heart: Cardiokines as Mediators of a Molecular Social Network</p> <p>11. Calcium Fluxes and Homeostasis</p> <p>12. Excitation-Contraction Coupling in the Heart</p> <p>13. Role of Sarcomeres in Cellular Tension, Shortening, and Signaling in Cardiac Muscle</p> <p>14. Cardiovascular Mechanotransduction</p> <p>15. Cardiomyocyte Metabolism: All Is in Flux</p> <p>16. Transcriptional Control of Striated Muscle Mitochondrial Biogenesis and Function</p> <p>17. Mitochondrial Morphology and Function</p> <p>18. Genetics and Genomics in Cardiovascular Gene Discovery</p> <p>19. Cardiovascular Proteomics: Assessment of Protein Post-Translational Modifications</p> <p>Section B: Adaptations and Response</p> <p>20. Adaption and Responses: Myocardial Innervations adn Neural Control</p> <p>21. Regulation of Cardiac Systolic Function and Contractility</p> <p>22. Intracellular Signaling Pathways in Cardiac Remodeling</p> <p>23. Oxidative Stress and Cardiac Muscle</p> <p>24. Physiologic and Molecular Responses of the Heart to Chronic Exercise</p> <p>25. Epigenetics in Cardiovascular Biology</p> <p>26. Cardiac MicroRNAs</p> <p>27. Protein Quality Control in Cardiomyocytes</p> <p>28. Cardioprotection</p> <p>29. Cardiac Fibrosis: Cellular and Molecular Determinants</p> <p>30. Autophagy in Cardiac Physiology and Disease</p> <p>31. Programmed Cardiomyocyte Death in Heart Disease</p> <p>32. Wnt and Notch: Potent Regulators of Cardiomyocyte Specification, Proliferation, and Differentiation</p> <p>Section C: Myocardial Disease</p> <p>33. Congenital Cardiomyopathies</p> <p>34. Genetics of Congenital Heart Disease</p> <p>35. Mechanisms of Stress-Induced Cardiac Hypertrophy</p> <p>36. Ischemic Heart Disease</p> <p>37. The Pathophysiology of Heart Failure</p> <p>38. The Right Ventricle: Reemergence of the Forgotten Ventricle</p> <p>39. Mammalian Myocardial Regeneration</p> <p>40. The Structural Basis of Arrhythmia</p> <p>41. Molecular and Cellular Mechanisms of Cardiac Arrhythmias</p> <p>42. Genetic Mechanisms of Arrhythmia</p> <p>43. Infiltrative adn Protein Misfolding Myocardial Diseases</p> <p>44. Cardiac Aging: From Humans to Molecules</p> <p>45. Adrenergic Receptor Polymorphisms in Heart Failure</p> <p>46. Cardiac Gene Therapy</p> <p>47. Protein Kinases in the Heart: Lessons Learned from Targeted Cancer Therapeutics</p> <p>48. Cell Therapy for Cardiac Disease</p> <p>49. Chemical Genetics of Cardiac Regeneration</p> <p>50. Device Therapy for Systolic Ventricular Failure</p> <p>51. Novel Therapeutic Targets and Strategies against Myocardial Diseases</p> <p>Part III: Skeletal Muscle</p> <p>Section A: Basic Physiology</p> <p>52. Skeletal Muscle Development</p> <p>53. Skeletal Muscle: Architecture of Membrane Systems</p> <p>54. The Vertebrate Neuromuscular Junction</p> <p>55. Neuromuscular Interactions that Control Muscle Function and Adaptation</p> <p>56. Control of Resting CA<SUP>2+ </SUP>Concentration in Skeletal Muscle</p> <p>57. Skeletal Muscle Excitation-Contraction Coupling</p> <p>58. The Contractile Machinery of Skeletal Muscle</p> <p>59. Skeletal Muscle Metabolism</p> <p>60. Skeletal Muscle Fiber Types</p> <p>Section B: Adaptations and Response</p> <p>61. Regulation of Skeletal Muscle Development and Function by microRNAs</p> <p>62. Musculoskeletal Tissue Injury and Repair: Role of Stem Cells, Their Differentiation, and Paracrine Effects</p> <p>63. Immunological Responses to Muscle Injury</p> <p>64. Skeletal Muscle Adaptation to Exercise</p> <p>65. Skeletal Muscle Regeneration</p> <p>66. Skeletal Muscle Dystrophin-Glycoprotein Complex and Muscular Dystrophy</p> <p>Section C: Skeletal Muscle Disease</p> <p>67. Statin-Induced Muscle Toxicity: Clinical and Genetic Determinants of Risk</p> <p>68. Myotonic Dystrophy</p> <p>69. Facioscapulohumeral Muscular Dystrophy: Unraveling the Mysteries of a Complex Epigenetic Disease</p> <p>70. ECM-Related Myopathies and Muscular Dystrophies</p> <p>71. Molecular Pathogenesis of Skeletal Muscle Abnormalities in Marfan Syndrome</p> <p>72. Diseases of the Nucleoskeleton</p> <p>73. Channelopathies of Skeletal Muscle Excitability</p> <p>74. Thick and Thin Filament Proteins: Acquired adn Hereditary Sarcomeric Protein Diseases</p> <p>75. Metabolic and Mitochondrial Myopathies</p> <p>Section D: Therapeutics</p> <p>76. Gene Therapy of Skeletal Muscle Disorders Using Viral Vectors</p> <p>77. Cell-Based Therapies in Skeletal Muscle Disease</p> <p>78. Immunological Components of Genetically Inherited Muscular Dystrophies: Duchenne Muscular Dystrophy and Limb-Girdle Muscular Dystrophy</p> <p>79. Myostatin: Regulation, Function, and Therapeutic Applications</p> <p>80. Insulin-Like Growth Factor I Regulation and Its Action in Skeletal Muscle Growth and Repair</p> <p>81. Novel Targets and Approaches to Treating Skeletal Muscle Disease</p> <p>Part IV: Smooth Muscle</p> <p>Section A: Basic Physiology</p> <p>82. Development of the Smooth Muscle Cell Lineage</p> <p>83. Smooth Muscle Myocyte Ultrastructure</p> <p>84. Potassium, Sodium, and Chloride Channels in Smooth Muscle Cells</p> <p>85. G-Protein-Coupled Receptors in Smooth Muscle</p> <p>86. Calcium Homeostasis and Signaling in Smooth Muscle</p> <p>87. Regulation of Smooth Muscle Contraction</p> <p>Section B: Heterogeneities</p> <p>88. Heterogeneity of Smooth Muscle</p> <p>89. Microcirculation</p> <p>90. Uterine Smooth Muscle</p> <p>Section C: Adaptations and Response</p> <p>91. Oxidative Stres, Endothelial Dysfunction, and Its Impact on Smooth Muscle Signaling</p> <p>92. Hemodynamic Control of Vascular Smooth Muscle Function</p> <p>93. Myogenic Tone and Mechanotransduction</p> <p>94. Cell-Cell Communication Through Gap Junctions</p> <p>95. Vascular Smooth Muscle Cell Phenotypic Adaptation</p> <p>96. Molecular Pathways of Smooth Muscle Disease</p> <p>Section D: Smooth Muscle Disease</p> <p>97. Genetic Variants in Smooth Muscle Contraction and Adhesion Genes Cause Thoracic Aortic Aneurysms and Dissections and Other Vascular Diseases</p> <p>98. Vascular Smooth Muscle Cell Remodeling in Atherosclerosis and Restenosis</p> <p>99. Arterial Hypertention</p> <p>100. Diabetic Vascular Disease</p> <p>101. Vascular Mechanisms of Hypertension in the Pathophysiology of Preeclampsia</p> <p>102. Erectile Dysfunction</p> <p>103. Smooth Muscle in the Normal and Diseased Pulmonary Circulation</p> <p>104. Airway Smooth Muscle and Asthma</p> <p>105. Aging</p> <p>106. Vascular Calcification</p> <p>107. Smooth Muscle Progenitor Cells: A Novel Target for the Treatment of Vascular Disease?</p> <p>108. Smooth Muscle: Novel Targets and Therapeutic Approaches</p>