Serpin Structure and Evolution

<p>1. Development of inhibitors of PAI-1</p> <p>Daniel Lawrence </p> <p>2. Kinetics of Serpin interactions with cofactors and proteases</p> <p>Steven Olson </p> <p>3. Fluorescence Correlation Spectroscopy (FCS) or Single molecule FRET</p> <p>Anne Gershenson </p> <p>4. Serpin-enzyme receptors (LRP)</p> <p>Dudley Strickland</p> <p>5. Predicting serpin / protease interactions</p> <p>Jiangning Song </p> <p>6. Serpins and autophagy</p> <p>David Perlmutter </p> <p>7. Plant Serpins</p> <p>Tom Roberts </p> <p>8. High throughput Drug discovery</p> <p>Bibek Gooptu </p> <p>9. Use of mouse models to study maspin function</p> <p>Ming Zhang </p> <p>10. The study of antitrypsin deficiency using animal models</p> <p>Jeffrey Teckman </p> <p>11. Use of Mouse Models to study PAI-1</p> <p>Paul Declerck </p> <p>12. Production of serpins using cell free systems</p> <p>Clifford Luke </p> <p>13. Studying serpin polymerisation in vitro</p> <p>James Huntington </p> <p>14. Serpins and neural function </p> <p>Denis Monard </p> <p>15. Probing serpin conformational change using mass spectrometry and related methods</p> <p>Patrick Wintrode </p> <p>16. Studying Serpin conformational change</p> <p>Randy Read </p> <p>17. Production of serpins in bacteria</p> <p>Mary Pearce </p> <p>18. Inhibition of cysteine proteases by serpins</p> <p>Jan Potempa </p> <p>19. Post transcriptional regulation of serpins</p> <p>Rob Medcalf </p> <p>20. Serpins and the complement system</p> <p>Rob Pike & Lakshmi Wijeyewickrema </p> <p>21. Serpins in Caenorhabditis elegans</p> <p>Stephen Pak & Gary Silverman </p> <p>22. PEDF and angiogenesis</p> <p>Patricia Becerra </p> <p>23. The Serpinb1 knockout mouse</p> <p>Charaf Benarafa </p> <p>24. Biophysical approaches to studying serpin folding</p> <p>Steve Bottomley </p> <p>25. TALS for studying the proteases inhibited by Serpins</p> <p>Chris Overall </p>