Jesus Giraldo,
Francisco Ciruela
Oligomerization in Health and Disease
Gebonden Engels 2013 9780123869319Verwachte levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.
Specificaties
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Inhoudsopgave
<p>Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization</p> <ol> <p> <li>Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization</li> <p> <li>Structural, Evolutionary and Assembly Principles of Protein Oligomerization</li> <p> <li>Physico-Chemical Principles of Protein Aggregation</li> <p> <li>Structural Aspects of Amyloid Formation</li> <p>Section II. Oligomerization in Seven-Transmembrane Receptors</p> <p> <li>Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers</li> <p> <li>Challenges in the Development of Heteromer-GPCR-Based Drugs</li> <p> <li>Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"</li> <p> <li>G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders</li> <p> <li>Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of Abuse</li> <p>Section III. Oligomerization in Ion Channels</p> <p> <li>Social Networking among Voltage-Gated Potassium Channels</li> <p> <li>Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy</li> <p> <li>Consequences of Dimerization of the Voltage Gated Proton Channel</li> <p> <li>Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate Receptors</li> <p>Section IV. Oligomerization in Enzymes</p> <p> <li>The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase</li> <p> <li>Oligomerization of Dynamin Superfamily Proteins in Health and Disease</li> <p> <li>Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications</li> <p> <li>Oligomerization in Endoplasmic Reticulum Stress Signaling</li> <p>Section V. Oligomerization in Regulatory Proteins</p> <p> <li>Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity</li> <p> <li>Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease</li> <p> <li>Chemokine Oligomerization in Cell Signaling and Migration</li> <p> <li>Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking</li> </ol>
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