John E. Macor
Annual Reports in Medicinal Chemistry
Paperback Engels 2012 9780123964922Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
Specificaties
Lezersrecensies
Wees de eerste die een lezersrecensie schrijft!
Inhoudsopgave
Personal Essay
- Reflections on Medicinal Chemistry at Merck, West Point Paul S. Anderson
- My Path in Seeking New Medicines Peter R. Bernstein
- Tales of Drug Discovery M. Ross Johnson I. Central Nervous System DiseasesSection Editor: Albert J. Robichaud; Sage Therapeutics, Inc. Cambridge, Massachusetts
- Recent Developments in Targeting Neuroinflammation in Disease Allen T. Hopper, Brian M. Campbell, Henry Kao, Sean A. Pintchovski and Roland G. W. Staal
- Secretase Inhibitors and Modulators as a Disease Modifying Approach Against Alzheimer’s Disease Harrie J. M. Gijsen and François P. Bischoff
- mGluR2 Activators and mGluR5 Blockers Advancing in the Clinic for Major CNS Disorders Sylvain Célanire, Guillaume Duvey, Sonia Poli and Jean-Philippe Rocher
- NMDA Antagonists of GluN2B Subtype and Modulators of GluN2A, GluN2C and GluN2D Subtypes – Recent Results and Developments Kamalesh B. Ruppa, Dalton King and Richard Olson
- Recent Advances in the Development of PET and SPECT Tracers for Brain Imaging Lei Zhang and Anabella Villalobos II. Cardiovascular and Metabolic DiseasesSection Editor: Andy Stamford, Merck Research Laboratories, Kenilworth, New Jersey
- Case History: EliquisTM (Apixaban), a Potent and Selective Inhibitor of Coagulation Factor Xa for the Prevention and Treatment of Thrombotic Diseases Donald J. P. Pinto, Pancras C. Wong, Robert M. Knabb and Ruth R. R. Wexler
- AMPK Activation in Health and Disease Iyassu K. Sebhat and Robert W. Myers
- Type-2 Diabetes and Associated Co-Morbidities as an Inflammatory Syndrome Juan C. Jaen, Jay P. Powers and Tim Sullivan
- Beyond PPARs & Metformin: New Insulin Sensitizers for the Treatment of Type 2 Diabetes Philip A. Carpino and David Hepworth III. Inflammatory Pulmonary and Gastrointestinal DiseasesSection Editor: David S. Weinstein, Bristol-Myers Squibb R&D, Princeton, New Jersey
- Recent Advances in the Discovery and Development of Sphingosine-1-Phosphate-1 Receptor Agonists Alaric J. Dyckman
- Bifunctional Compounds for the Treatment of COPD Gary Phillips and Michael Salmon
- Inflammatory Targets for the Treatment of Atherosclerosis Robert O. Hughes, Alessandra Bartolozzi and Hidenori Takahashi IV. OncologySection Editor: Shelli R. McAlpine, School of Chemistry, University of New South Wales, Sydney, Australia
- Nanotechnology Therapeutics in Oncology – Recent Developments and Future Outlook Paul F. Richardson
- Small-Molecule Antagonists of Bcl-2 Family Proteins Sean P. Brown and Joshua P. Taygerly
- Notch Pathway Modulators as Anti-Cancer Chemotherapeutics Vibhavari Sail and M. Kyle Hadden
- Anaplastic Lymphoma Kinase (ALK) Inhibitors for the Treatment of ALK-Positive Cancers Kazutomo Kinoshita, Nobuhiro Oikawa and Takuo Tsukuda V. Infectious DiseasesSection Editor: John Primeau, Westford, Massachusetts
- Recent Advances in the Discovery of Dengue Virus Inhibitors Jeremy Green, Upul Bandarage, Kate Luisi and Rene Rijnbrand
- Non Fluoro-Quinolone Based Inhibitors of Mycobacterial Type II Topoisomerase as Potential Therapeutic Agents for TB Pravin S. Shirude and Shahul Hameed
- HCV Inhibition Mediated through the Nonstructural Protein 5A (NS5A) Replication Complex Robert Hamatake, Andrew Maynard and Wieslaw M. Kazmierski VI. Topics in BiologySection Editor: John Lowe, JL3Pharma LLC, Stonington, Connecticut
- Antibody-Drug Conjugates for Targeted Cancer Therapy Victor S. Goldmacher, Thomas Chittenden, Ravi V. J. Chari, Yelena V. Kovtun and John M. Lambert
- 3D Cell Cultures: Mimicking in Vivo Tissues for Improved Predictability in Drug Discovery Indira Padmalayam and Mark J. Suto
- Virally Encoded G Protein-Coupled Receptors: Overlooked Therapeutic Opportunities? Nuska Tschammer
- Recent Advances in Wnt/b-Catenin Pathway Small Molecule Inhibitors Daniel D. Holsworth and Stefan Krauss VII. Topics in Drug Design and DiscoverySection Editor: Peter R. Bernstein, PhaRmaB LLC, Rose Valley, Pennsylvania
- Targeted Covalent Enzyme Inhibitors Mark C. Noe and Adam M. Gilbert
- Drug Design Strategies for GPCR Allosteric Modulators P. Jeffrey Conn, Scott D. Kuduk and Darío Doller
- Progress in the Development of Non-ATP Competitive Protein Kinase Inhibitors for Oncology Campbell McInnes VIII. TrendsSection Editor: Joanne Bronson, Bristol-Myers Squibb, Wallingford, Connecticut
- New Chemical Entities Entering Phase III Trials in 2011 Gregory T. Notte
- To Market, To Market – 2011Joanne Bronson, Murali Dhar, William Ewing and Nils Lonberg
Rubrieken
- advisering
- algemeen management
- coaching en trainen
- communicatie en media
- economie
- financieel management
- inkoop en logistiek
- internet en social media
- it-management / ict
- juridisch
- leiderschap
- marketing
- mens en maatschappij
- non-profit
- ondernemen
- organisatiekunde
- personal finance
- personeelsmanagement
- persoonlijke effectiviteit
- projectmanagement
- psychologie
- reclame en verkoop
- strategisch management
- verandermanagement
- werk en loopbaan