K. Dane Wittrup,
Gregory L. Verdine
Protein Engineering for Therapeutics, Part B
Gebonden Engels 2012 9780123969620Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds
Specificaties
ISBN13:9780123969620
Taal:Engels
Bindwijze:Gebonden
Uitgever:Elsevier Science
Serie:Methods in Enzymology
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Inhoudsopgave
Part III: Peptides <br>1. Stapled Peptides for Intracellular Drug Targets<br>2. Mapping of vascular zip codes by phage display<br>3. Engineering cyclic peptide toxins<br>4. Peptide Discovery using Bacterial Display and Flow Cytometry <br><br>Part V: Scaffolds <br>5. Designed Ankyrin Repeat Proteins (DARPins): From research to therapy <br>6. Target-binding proteins based on the tenth human fibronectin type III domain (10Fn3) <br>7. Anticalins: small engineered binding proteins based on the lipocalin scaffold<br>8. T Cell Receptor Engineering <br>9. Engineering Knottins as Novel Binding Agents <br><br>Part VI: Pharmacokinetics <br>10. Practical Theoretic Guidance for the Design of Tumor Targeting Agents <br>11. Re-Engineering Biopharmaceuticals for Targeted Delivery Across the Blood-Brain Barrier <br>12. Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells
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