Toxicogenomics-Based Cellular Models

Alternatives to Animal Testing for Safety Assessment

Gebonden Engels 2014 9780123978622
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Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

Specificaties

ISBN13:9780123978622
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

<p>Chapter 1. Introduction and Scoping<br>Chapter 2. Genotoxicity and Carcinogenesis<br>Chapter 3. Immunotoxicity<br>Chapter 4. Reproduction Toxicity<br>Chapter 5. Organ Toxicity<br>Chapter 6. Toxicoinformatics<br>Chapter 7. Validating Toxicogenomics Assays<br>Chapter 8. Implementation Outlook</p>

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        Toxicogenomics-Based Cellular Models