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A Pharmacology Primer

Techniques for More Effective and Strategic Drug Discovery

Gebonden Engels 2014 9780124076631
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Samenvatting

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research.

Specificaties

ISBN13:9780124076631
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

Chapter 1 – What is Pharmacology?Chapter 2 – How Different Tissues Process Drug ResponseChapter 3 – Drug Receptor TheoryChapter 4 – Pharmacological Assay Formats: BindingChapter 5 – Agonists: The Measurement of Affinity and Efficacy in Functional AssaysChapter 6 – Orthosteric Drug AntagonismChapter 7 – Allosteric Drug InteractionsChapter 8 – Drug DiscoveryChapter 9 – Drug Development: Pharmacokinetics and Safety PharmacologyChapter 10 – Target-and System-based Strategies for Drug DiscoveryChapter 11 – Lead Optimization: Data-Driven AnalysisChapter 12 – Statistics and Experimental DesignChapter 13 – Selected Pharmacological MethodsChapter 14 – Exercises in Pharmacodynamics and PharmacokineticsGlossary of Pharmacological TermsAppendicesStatistical TablesMathematical Fitting Functions

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€ 120,94
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        A Pharmacology Primer