G Protein Coupled Receptors

Modeling, Activation, Interactions and Virtual Screening

Gebonden Engels 2013 9780124078659
€ 194,75
Levertijd ongeveer 9 werkdagen
Gratis verzonden

Samenvatting

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers G protein coupled receptors, and includes chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation.

Lezersrecensies

Wees de eerste die een lezersrecensie schrijft!

Inhoudsopgave

GPCR Modeling
  1. The Protein Local Optimization Program and G-Protein Coupled Receptors: Loop Restoration and Applications to Homology Modeling
  2. Modeling Active GPCR Conformations
  3. Molecular Modeling of Adenosine Receptors
  4. Predicting G Protein-Coupled Receptors Families using Different Physiochemical Properties and Pseudo Amino Acid Composition Computational Design and Experimental Characterization of GPCR Segment ModelsGPCR Interactions with Other Molecules and Cross-Talk
  5. G Protein-Coupled Receptor Interaction with Small GTPases
  6. Quantification of Receptor Tyrosine Kinase Activation and Transactivation by G Protein Coupled Receptors Using Spatial Intensity Distribution Analysis (SpIDA)
  7. NMR Methods for Detection of Small Molecule Binding to RGS4
  8. Group II Activators of G-protein Signaling: Monitoring the Interaction of Ga with the G-Protein Regulatory Motif in the Intact Cell
  9. Homogeneous Time-Resolved Fluorescence Assay to Probe Folded G Protein-Coupled Receptors
  10. cAMP Biosensors Applied in Molecular Pharmacological Studies of G Protein-Coupled Receptors
  11. Rhodopsin-Lipid Interactions Studied by NMR
  12. GPCR Bias
  13. Biasing the Parathyroid Hormone Receptor: Relating In Vitro Ligand Efficacy to In Vivo Biological Activity
  14. Virtual Screening
  15. Application of Monte Carlo-based Receptor-Ensemble Docking to Virtual Screening for GPCR Ligands
  16. From Heptahelical Bundle to Hits from the Haystack: Structure-Based Virtual Screening for GPCR Ligands
  17. GPCR Activation
  18. Kinetics and Dynamics in the G-Protein Coupled Receptor Signaling Cascade
  19. Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy of G Protein-Coupled Receptors
  20. Post-Translation Modification of G Protein-Coupled Receptor in Relationship to Biased Agonism
  21. Protein S-Nitrosylation Measurement

Managementboek Top 100

€ 194,75
Levertijd ongeveer 9 werkdagen
Gratis verzonden

Rubrieken

    Personen

      Trefwoorden

        Artikelen

          G Protein Coupled Receptors