G Protein Coupled Receptors
Modeling, Activation, Interactions and Virtual Screening
Gebonden Engels 2013 9780124078659Samenvatting
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers G protein coupled receptors, and includes chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation.
Specificaties
Lezersrecensies
Inhoudsopgave
- The Protein Local Optimization Program and G-Protein Coupled Receptors: Loop Restoration and Applications to Homology Modeling
- Modeling Active GPCR Conformations
- Molecular Modeling of Adenosine Receptors Predicting G Protein-Coupled Receptors Families using Different Physiochemical Properties and Pseudo Amino Acid Composition Computational Design and Experimental Characterization of GPCR Segment ModelsGPCR Interactions with Other Molecules and Cross-Talk
- G Protein-Coupled Receptor Interaction with Small GTPases
- Quantification of Receptor Tyrosine Kinase Activation and Transactivation by G Protein Coupled Receptors Using Spatial Intensity Distribution Analysis (SpIDA)
- NMR Methods for Detection of Small Molecule Binding to RGS4
- Group II Activators of G-protein Signaling: Monitoring the Interaction of Ga with the G-Protein Regulatory Motif in the Intact Cell
- Homogeneous Time-Resolved Fluorescence Assay to Probe Folded G Protein-Coupled Receptors
- cAMP Biosensors Applied in Molecular Pharmacological Studies of G Protein-Coupled Receptors
- Rhodopsin-Lipid Interactions Studied by NMR GPCR Bias
- Biasing the Parathyroid Hormone Receptor: Relating In Vitro Ligand Efficacy to In Vivo Biological Activity Virtual Screening
- Application of Monte Carlo-based Receptor-Ensemble Docking to Virtual Screening for GPCR Ligands
- From Heptahelical Bundle to Hits from the Haystack: Structure-Based Virtual Screening for GPCR Ligands GPCR Activation
- Kinetics and Dynamics in the G-Protein Coupled Receptor Signaling Cascade
- Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy of G Protein-Coupled Receptors
- Post-Translation Modification of G Protein-Coupled Receptor in Relationship to Biased Agonism
- Protein S-Nitrosylation Measurement
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