G Protein Coupled Receptors

<p>GPCR Modeling</p> <ol> <p> <li>The Protein Local Optimization Program and G-Protein Coupled Receptors: Loop Restoration and Applications to Homology Modeling</li> <li>Modeling Active GPCR Conformations</li> <li>Molecular Modeling of Adenosine Receptors</li> <li>Predicting G Protein-Coupled Receptors Families using Different Physiochemical Properties and Pseudo Amino Acid Composition</li> <p>Computational Design and Experimental Characterization of GPCR Segment Models</p> <p>GPCR Interactions with Other Molecules and Cross-Talk</p> <p> <li>G Protein-Coupled Receptor Interaction with Small GTPases</li> <li>Quantification of Receptor Tyrosine Kinase Activation and Transactivation by G Protein Coupled Receptors Using Spatial Intensity Distribution Analysis (SpIDA)</li> <li>NMR Methods for Detection of Small Molecule Binding to RGS4</li> <li>Group II Activators of G-protein Signaling: Monitoring the Interaction of Ga with the G-Protein Regulatory Motif in the Intact Cell</li> <li>Homogeneous Time-Resolved Fluorescence Assay to Probe Folded G Protein-Coupled Receptors</li> <li>cAMP Biosensors Applied in Molecular Pharmacological Studies of G Protein-Coupled Receptors</li> <li>Rhodopsin-Lipid Interactions Studied by NMR</li> <p>GPCR Bias</p> <p> <li>Biasing the Parathyroid Hormone Receptor: Relating In Vitro Ligand Efficacy to In Vivo Biological Activity</li> <p>Virtual Screening</p> <p> <li>Application of Monte Carlo-based Receptor-Ensemble Docking to Virtual Screening for GPCR Ligands</li> <li>From Heptahelical Bundle to Hits from the Haystack: Structure-Based Virtual Screening for GPCR Ligands</li> <p>GPCR Activation</p> <p> <li>Kinetics and Dynamics in the G-Protein Coupled Receptor Signaling Cascade</li> <li>Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy of G Protein-Coupled Receptors</li> <li>Post-Translation Modification of G Protein-Coupled Receptor in Relationship to Biased Agonism</li> <li>Protein S-Nitrosylation Measurement</li></ol>