Practical Biostatistics
A Friendly Step-by-Step Approach for Evidence-based Medicine
Paperback Engels 2012 9780124157941Samenvatting
Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials.
Specificaties
Lezersrecensies
Inhoudsopgave
PART 2 - OBSERVATIONAL STUDIES 4. Determination of association strength between an exposure factor and an event in observational studies5. Increasing accuracy in observational studies
PART 3 - STEP-BY-STEP BIOSTATISTICS OF A CLINICAL TRIAL6. STEP 1: Investigator's hypothesis and expression of its corresponding outcome7. STEP 2: n estimation and n assessment of a published trial8. STEP 3: Organization of variables and endpoints9. STEP 4: Measures for results expression of a clinical trial10. STEP 5: Determination of normality or non-normality of data distribution 11. STEP 6: Hypothesis testing12. STEP 7: Correlating sample data with the general population - 95% confidence Interval
PART 4 - ADDITIONAL CONCEPTS IN BIOSTATISTICS13. Individual and collective benefit and risk indexes inferable from intervention cohort studies14. Statistical assessment of diagnostic tests for the clinic15. Systematic reviews and meta-analyses16. Correlation and regression17. Per protocol analysis and intention to treat analysis
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