Gap Junctions in the Brain
Physiological and Pathological Roles
Gebonden Engels 2012 9780124159013Samenvatting
Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.
Specificaties
Lezersrecensies
Inhoudsopgave
Section II: Gap junctions between astrocytes, neurons, and glia-neuron interactions
Section III: The role of gap junctions in brain development, neurogenesis and synaptic plasticity
Section IV: Gap junctions and neuronal synchronization
Section V: Gap junctions and neurological and neuropsychiatric diseases
Section VI: Gap junctions and behavior
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