Protein Engineering for Therapeutics, Part A

<ol> <li>Simplified Synthetic Antibody Libraries</li> <p> <li>Generation of Dual Variable Domain Immunoglobulin Molecules for Dual-specific Targeting</li> <p></p> <li>Discovery of internalizing antibodies to tumor antigens from phage libraries</li> <p></p> <li>Optimizing properties of anti-receptor antibodies using kinetic computational models and experiments</li> <p></p> <li>Cell-specific siRNA delivery by peptides and antibodies</li> <p></p> <li>Conjugation of Anticancer Drugs Through Endogenous Monoclonal Antibody Cysteine Residues</li> <p></p> <li>Building and characterizing antibody-targeted lipidic nanotherapeutics</li> <p></p> <li>Cell-Targeting Fusion Constructs Containing Recombinant Gelonin</li> <p></p> <li>Stapled Peptides for Intracellular Drug Targets</li> <p></p> <li>Mapping of vascular zip codes by phage display</li> <p></p> <li>Engineering cyclic peptide toxins</li> <p></p> <li>Peptide Discovery using Bacterial Display and Flow Cytometry</li> <p></p> <li>Oral enzyme therapy for celiac sprue</li> <p></p> <li>Rational Design and Evaluation of Mammalian Ribonuclease Cytotoxins</li> <p></p> <li>Engineering Reduced-Immunogenicity Enzymes for Amino Acid Depletion Therapy in Cancer</li> <p></p> <li>Designed Ankyrin Repeat Proteins (DARPins): From research to therapy</li> <p></p> <li>Target-binding proteins based on the tenth human fibronectin type III domain (¹⁰Fn3)</li> <p></p> <li>Anticalins: small engineered binding proteins based on the lipocalin scaffold</li> <p></p> <li>T Cell Receptor Engineering</li> <p></p> <li>Engineering Knottins as Novel Binding Agents</li> <p></p> <li>Re-Engineering Biopharmaceuticals for Targeted Delivery Across the Blood-Brain Barrier</li> <p></p> <li>Practical Theoretic Guidance for the Design of Tumor Targeting Agents</li> <p></p> <li>Fusions of elastin-like polypeptides to pharmaceutical proteins</li> <p></p> <li>Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells</li> <p></p></ol>