G Protein-Coupled Receptors

Signaling, Trafficking and Regulation

Gebonden Engels 2016 9780128035955
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G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation.

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ISBN13:9780128035955
Taal:Engels
Bindwijze:Gebonden

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Section 1 Trafficking, Localization and Imaging of GPCRs<br>1. Localization and Signaling of GPCRs in Lipid Rafts<br>Van Anthony M. Villar, Santiago G. Cuevas, Xiaoxu Zheng, Pedro A. Jose<br>2. Imaging GPCRs Trafficking and Signaling with Total Internal Reflection Fluorescence Microscopy in Cultured Neurons<br>Francheska Delgado-Peraza, Carlos Nogueras-Ortiz,  Agnes M. Acevedo Canabal, Cristina Roman-Vendrell, Guillermo A. Yudowski<br>3. Trafficking of Ciliary G-Protein Coupled Receptors<br>Jeremy McIntyre, Mellisa M. Hege, Nicolas F. Berbari<br>4. Single Molecule Resolution of G Protein-Coupled Receptor (GPCR) Complexes<br>Kim C Jonas, Ilpo Huhtaniemi, Aylin C Hanyaloglu<br>5. Quantification of the mRNA Expression of G-protein Coupled Receptors in Human Adipose Tissue<br>Stefan Amisten<br>Section 2 Signaling and Regulation of GPCRs<br>6. Studying the Regulation of Endosomal cAMP Production in GPCR Signaling<br>Alexandre Gidon, Timothy N. Feinstein, Kunhong Xiao, Jean-Pierre Vilardaga<br>7. GPCR-Radioligand Binding Assays<br>Colleen A. Flanagan<br>8. Assessing Smoothened-Mediated Hedgehog Signaling in Zebrafish<br>Teresa Casar Tena, Melanie Philipp<br>9. GPCRs and Actin-Cytoskeleton Dynamics<br>Genaro Vázquez-Victorio, Claudia González-Espinosa, Zyanya P. Espinosa-Riquer, Marina Macías-Silva<br>Section 3 Cellular Assays for GPCRs<br>10. Olfactory Receptor Signaling <br>Gabriela Antunes, Fabio Marques Simoes de Souza<br>11. Tracking GPCR Biosynthesis and Degradation Using a Non-Radioactive Pulse Chase Methodology<br>Richard B. Vallee Richard Wargachuk, Dominic Devost, Cynthia Zhou, Terence E. Hébert<br>12. Tango Assay for Ligand Induced GPCR - β-arrestin2 Interaction: Application in Drug Discovery<br>Shalini Dogra, Chandan Sona, Ajeet Kumar, Prem N Yadav<br>13. Resonance Energy Transfer-Based Approaches to Study GPCRs <br>Mohammed Akli Ayoub<br>14. Quantitative Analysis of G Protein-Coupled Receptor Internalization Using DnaE Intein-Based Assay<br>Bin Lu, Linjie Chen, Yaping Zhang, Ying Shi, Naiming Zhou<br>15. Cellular and Subcellular Context Determine Outputs from Signalling Biosensors<br>Dominic Devost, Nicolas Audet, Cynthia Zhou, Hiroyuki Kobayashi, Hélène Bonin, Viktorya Lukashova, Christian Le Gouill, Michel Bouvier, Terence E. Hébert<br>Section 4 Structural and Computational Investigation of GPCRs<br>16. Protease-Activated Receptors PARs in Cancer: Novel Biased Signaling and Targets for Therapy<br>Bar-Shavit R, Maoz M, Kancharla A, Jaber M, Agranovich D, Grisaru-Granovsky S, Uziely B<br>17. Computational Methods for Studying G Protein-Coupled Receptors (GPCRs)<br>Agnieszka A. Kaczor, Ewelina Rutkowska, Damian Bartuzi, Katarzyna M. Targowska-Duda, Dariusz Matosiuk, Jana Selent<br>18. Comparing Class A GPCRs to Bitter Taste Receptors: Structural Motifs, Ligand Interactions and Agonist-to-Antagonist Ratios<br>Antonella Di Pizio, Anat Levit, Michal Slutzki, Maik Behrens, Rafik Karaman, Masha Y Niv<br>19. What Can Simulations Tell Us About GPCRs: Integrating the Scales<br>Durba Sengupta, Manali Joshi, Chaitanya A. Athale, Amitabha Chattopadhyay

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