The Autoimmune Diseases

<p>Section 1: Immunologic Basis of Autoimmunity<br>1. Prelude: Historical introduction to autoimmunity and autoimmune disease<br>2. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity<br>3. General Features of Autoimmune Diseases<br>4. Antigen Presentation, Dendritic Cells, and Autoimmunity<br>5. T cells and their subsets<br>6. Role of Th1 Th2 Th17 Cells in Autoimmunity<br>7. Tolerance and Autoimmunity: T Cells<br>8. Regulatory T Cells<br>9. B Cells and Autoimmunity<br>10. Immunological memory T cells<br>11. Immunological memory B cells 12. Apoptotic Cells as a Source of Autoantigens<br>13. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes<br>14. Functional Effects of Autoantibodies<br>15. Cytokine Chemokines<br>16. Signaling Pathways in T and B Lymphocytes<br>17. HLA Genetics and Autoimmunity<br>18. Non HLA Genetics<br>19. AIRE related Autoimmunity<br>20. Immune Deficiencies and Autoimmunity<br>21. Infections and Autoimmunity<br>22. Noninfectious Environmental Agents and Autoimmunity<br>23. Sex, Pregnancy and Autoimmunity<br>24. Animal Models of Autoimmune Disease</p> <p>Section 2: Multisystem Diseases<br>25. Systemic Lupus Erythematosus <br>26. Systemic Sclerosis, Scleroderma<br>27. Antiphospholipid Syndrome<br>28. Sjogren Syndrome<br>29. Rheumatoid Arthritis<br>30. Spondyloarthritis and Chronic Idiopathic Arthropathies<br>31. Myositis<br>32. Thyroid Disease<br>33. Type 1 Diabetes<br>34. Adrenalitis<br>35. Polyendocrine Syndromes<br>36. Gastritis and Pernicious Anemia<br>37. Hypophysitis<br>38. Hemolytic Anemia<br>39. Thrombocytopenic Purpura<br>40. Neutropenia<br>41. Aplastic Anemia<br>42. Clotting Disorders<br>43. Multiple Sclerosis<br>44. Peripheral Neuropathy<br>45. Myasthenia Gravis<br>46. Ocular Disease<br>47. Inner Ear Disease<br>48. Celiac Disease<br>49. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease<br>50. Chronic Hepatitis<br>51. Primary Billiary Cirrhosis<br>52. Primary Sclerosing Cholangitis<br>53. Pancreatitis<br>54. Bullous Skin Diseases: Pemphigus and Pemphigoid<br>55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria<br>56. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis<br>57. Orchitis and Male Infertility<br>58. Oophoritis<br>59. Rheumatic Heart Disease<br>60. Myocarditis and Dilated Cardiomyopathy<br>61. Necrotizing Arteritis and Small Vessel Vasculitis<br>62. Large and Medium Vessel Vasculitides<br>63. Autoimmune Disorders of the Lung<br>64. Paraneoplastic Diseases<br>65. Antibody-Associated Neurological Diseases<br>66. Autoinflammatory and other Related Diseases</p> <p>Section 3: Diagnosis, Prevention, and Therapy<br>67. Autoantibody Assays, Testing, and Standardization <br>68. Prediction of Autoimmune Disease<br>69. Emerging Therapies for Autoimmune Diseases<br>70. Postlude</p>