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Organoids and Mini-Organs

Paperback Engels 2018 9780128126363
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Samenvatting

Organs and Mini-Organs combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future directions and specific problems that need to be solved.

Specificaties

ISBN13:9780128126363
Taal:Engels
Bindwijze:Paperback
Aantal pagina's:284

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Inhoudsopgave

PART I INTRODUCTION
1. Organoids and mini-organs: Introduction, history, and potential


PART II CONSTRUCTING ORGANOIDS
2. Elements of organoid design
3. Intestinal organoids: Mini-guts grown in the laboratory
4. Three-dimensional breast culture models
5. Prostate organoids: Directed differentiation from embryonic stem cells
6. Kidney organoids
7. Spontaneous self-assembly of liver organoids from differentiated human cells
8. Cerebral organoids: Building brains from stem cells
9. From organoids to mini-organs: A case study in the kidney


PART III APPLICATIONS OF ORGANOIDS
10. Intestinal organoids: A model for biomedical and nutritional research
11. A three-dimensional neurosphere system using human stem cells for nanotoxicology studies
12. Organoids for modeling kidney disease
13. Intestinal organoids in studying host2bacterial interactions
14. Four challenges for organoid engineers

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