Chromatin Signaling and Neurological Disorders

Gebonden Engels 2019 9780128137963
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases.

In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

Specificaties

ISBN13:9780128137963
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

<p>1. Chromatin and epigenetic signaling pathways<br>2. Non-pathologic neurological development<br>3. Spinal muscular atrophy<br>4. Triplet-Repeat Neurological Diseases<br>5. Amyotrophic Lateral Sclerosis<br>6. Charcot-Marie-Tooth disease<br>7. Parkinson's disease<br>8. Huntington's disease<br>9. Multiple Sclerosis<br>10. Ataxia Telangiectasia<br>11. Cockayne Syndrome neurodevelopmental disorders<br>12. Angelman Syndrome and Prader-Willi Syndrome<br>13. Rett Syndrome<br>14. Rubinstein-Taybi Syndrome<br>15. Sotos Syndrome<br>16. ATRX<br>17. Fragile X syndrome and mental retardation<br>18. Autism Spectrum Disorder and Asperger Syndrome<br>19. Schizophrenia<br>20. Gilles de la Tourette Syndrome<br>21. Alzheimer's disease (and other dementias)<br>22. Mood disorders<br>23. Attention deficit hyperactivity disorder (ADHD)<br>24. Obsessive compulsive disorder (OCD)</p>

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        Chromatin Signaling and Neurological Disorders