GPCRs

<p>Part I GPCR structure<br>1. Progress in GPCR structure Determination<br>2. Structure, function and therapeutic potential of adhesion GPCRs<br>3. Structural diversity in ligand recognition by GPCRs<br>4. NMR-based approaches to the study of GPCRs and GPCR-ligand interactions<br>5. Supramolecular structure of opsins<br>6. Molecular determinants of GPCR oligomerization<br>7. Structure of G-protein-coupled receptor heteromers<br>8. Class A GPCR oligomerization: reasons of controversy</p> <p>Part II GPCR function<br>9. Quantifying GPCR allostery and biased signaling<br>10. Kinetics of ligand binding and signaling<br>11. Allosteric modulators targeting GPCRs<br>12. Arrestin-mediated signaling at GPCRs<br>13. Organellar Gbγ signaling - GPCR signaling beyond the cell surface</p> <p>Part III GPCRs in disease and targeted drug discovery<br>14. G protein-coupled receptor allosteric modulators: understanding modulator affinity and pharmacological dose<br>15. Computer-aided GPCR drug discovery<br>16. Tackling the complexities of orphan GPCR ligand discovery with rationally assisted approaches<br>17. G protein-coupled receptors in neurodegenerative diseases<br>18. GPCR targets in type 2 diabetes<br>19. GPCRs in thromboinflammation and hemostasis<br>20. Angiotensin II receptors: structure-function and drug discovery<br>21. GPCRs in innate and adaptive immune responses<br>22. Role of GPCRs in cancer</p>