Retinoid Signaling Pathways

Gebonden Engels 2020 9780128201442
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Samenvatting

Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.

Specificaties

ISBN13:9780128201442
Taal:Engels
Bindwijze:Gebonden
Aantal pagina's:610

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Inhoudsopgave

    1. Vitamin A and its natural derivatives
    2. Chris P.F. Redfern
    3. Post-natal all-trans-retinoic acid biosynthesis
    4. Joseph L. Napoli
    5. Retinoid metabolism and functions mediated by retinoid binding-proteins
    6. Joseph L. Napoli and Hong Sik Yoo
    7. Generation and isolation of recombinant retinoid oxidoreductase complex
    8. Mark K. Adams, Olga V. Belyaeva and Natalia Y. Kedishvili
    9. Sample preparation for structural and functional analyses of the STRA6 receptor for retinol-binding protein
    10. Brianna K. Costabile, Youn-Kyung Kim, Yunting Chen, Oliver B. Clarke, Loredana Quadro and Filippo Mancia
    11. Use of fixatives for immunohistochemistry and their application for detection of retinoic acid synthesizing enzymes in the central nervous system
    12. Azita Kouchmeshky and Peter McCaffery
    13. Classical pathways of gene regulation by retinoids
    14. Ehmke Pohl and Charles W.E. Tomlinson
    15. Protein-protein interactions in the regulation of RAR–RXR heterodimers transcriptional activity
    16. Albane le Maire, Pierre Germain and William Bourguet
    17. Natural ligands of RXR receptors
    18. Patricia García, Paula Lorenzo and Angel R. de Lera
    19. DNA recognition by retinoic acid nuclear receptors
    20. Carole Peluso-Iltis, Judit Osz and Natacha Rochel
    21. Noncanonical retinoic acid signaling
    22. Jennifer Nhieu, Yu-Lung Lin and Li-Na Wei
    23. Retinoic acid and microRNA
    24. Lijun Wang, Atharva Piyush Rohatgi and Yu-Jui Yvonne Wan
    25. Analysis of vitamin A and retinoids in biological matrices
    26. Lindsay C. Czuba, Guo Zhong, King Yabut and Nina Isoherranen
    27. Effects of vitamin A and retinoic acid on mouse embryonic stem cells and their differentiating progeny
    28. Mary Ann Asson-Batres and Christopher W. Norwood
    29. Identifying vitamin A signaling by visualizing gene and protein activity, and by biochemical isolation of vitamin A metabolites
    30. Stephen R. Shannon, Jianshi Yu, Amy E. Defnet, Danika Bongfeldt, Alexander R. Moise, Maureen A. Kane and Paul A. Trainor
    31. Whole mount in situ hybridization and immunohistochemistry for studying retinoic acid signaling in developing amphioxus
    32. Matteo Bozzo, Simona Candiani and Michael Schubert
    33. Design of synthetic retinoids
    34. David R. Chisholm and Andrew Whiting
    35. Application of human organotypic skin raft cultures for analysis of retinoid metabolism, retinoic acid signaling, and screening of bioactive rexinoids
    36. Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili and Olga V. Belyaeva
    37. Tissue localization of retinoic acid receptor (RAR) active drugs
    38. Azita Kouchmeshky, Timothy Goodman, Andy Whiting and Peter McCaffery
    39. The development of methodologies for high-throughput retinoic acid binding assays in drug discovery and beyond
    40. Charles W.E. Tomlinson and Andrew Whiting
    41. Using the human CYP26A1 gene promoter as a suitable tool for the determination of RAR-mediated retinoid activity


Reza Zolfaghari, Floyd J. Mattie, Cheng-Hsin Wei, David R. Chisholm, Andrew Whiting and A. Catharine Ross

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€ 188,50
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          Retinoid Signaling Pathways