Connectomic Deep Brain Stimulation

Paperback Engels 2021 9780128218617
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Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. 

This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery.

Specificaties

ISBN13:9780128218617
Taal:Engels
Bindwijze:Paperback

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Inhoudsopgave

Part I: Deep Brain Stimulation and Connectomics – A Fruitful Marriage?<br>1. Deep Brain Stimulation – an Introduction<br>2. The “connectomic revolution” in the field of neuroimaging<br>3. The mechanism of deep brain stimulation<br>Part II: DBS Imaging Methods<br>4. DBS Imaging - An Overview<br>5. DBS Imaging Methods I: Preprocessing<br>6. DBS Imaging Methods II: Electrode Localization<br>7. DBS Imaging Methods III: Estimating the electric field and Volume of Tissue Activated<br>8. DBS Imaging Methods IV: Stereotactic Spaces<br>9. DBS Imaging Methods IV: Group Analyses<br>Part III: Connectomics in DBS<br>10. Resting-State functional MRI based Connectivity<br>11. Diffusion-weighted MRI based Connectivity<br>12. Normative Connectomes and their use in DBS<br>13. Investigating Network Effects of DBS with fMRI<br>14. High-Resolution Resources and Histological Mesh Tractography<br>15. Using brain lesions to inform connectomic DBS<br>16. Electrophysiological connectivity measures from DBS-targets in Parkinson’s disease and Dystonia<br>Part IV: Applications of Connectomic DBS<br>17. Predicting treatment response on a local level<br>18. Predicting treatment response based on DBS connectivity<br>19. Connectomic DBS in Parkinson’s Disease, Essential Tremor and Dystonia<br>20. Connectomic DBS in Major Depression<br>21. Connectomic DBS in Obsessive Compulsive Disorder<br>22. Connectomics in the Operation Room<br>23. Investigating cognitive neuroscience concepts using connectomic DBS<br>24. Combining invasive and noninvasive neuromodulation techniques via connectomics<br>Part V: Outlook<br>25. Outlook: Toward Personalized Connectomic Deep Brain Stimulation<br>26. Whole-brain modelling to predict optimal DBS targeting <br>

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€ 185,80
Levertijd ongeveer 9 werkdagen
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        Connectomic Deep Brain Stimulation