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Diagnostic Pathology : Hepatobiliary and Pancreas

Gebonden Engels 2021 9780323776202
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic and nonneoplastic diseases of the digestive tract and accessory organs such as the pancreas and liver, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, Diagnostic Pathology: Hepatobiliary and Pancreas is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.

Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls. 

Features thorough updates throughout, including novel immunohistochemical markers and other ancillary techniques (such as BAP1, INSM1, Rb, albumin in situ hybridization) that play an increasingly critical role in improving diagnoses 

Addresses recent advances in molecular pathology—new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as new details about the genesis and activity of tumors in the liver, pancreas, and biliary systems 

Includes details from the 2019 WHO Classification of Tumors of the Digestive System regarding important changes to diagnostic techniques, identification of new variants of cancers, and immunohistochemical markers and ancillary techniques that improve diagnosis and treatment options 

Reflects recent WHO updates and updates from the AJCC’s 8th Edition Cancer Staging Manual such as new terminology, new grading of neuroendocrine tumors and neuroendocrine carcinomas, and characteristic molecular alterations in hepatocellular adenoma, cholangiocarcinoma, and other tumors 

Uses a templated page layout, bulleted text, and a generous number of high-quality images to help practicing and in-training pathologists reach a confident diagnosis 

Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

Specificaties

ISBN13:9780323776202
Taal:Engels
Bindwijze:Gebonden

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Inhoudsopgave

<p>SECTION 1: LIVER</p> <p>INHERITED, METABOLIC, AND DEVELOPMENTAL DISORDERS</p> <p>4 Glycogen Storage Disease, Hepatic<br>Joseph Misdraji, MD, Lisa Yerian, MD, and Grace E. Kim, MD<br>10 Tyrosinemia<br>Joseph Misdraji, MD<br>12 Niemann-Pick Disease<br>Joseph Misdraji, MD<br>14 Gaucher Disease<br>Joseph Misdraji, MD<br>16 Neonatal Hemochromatosis<br>Joseph Misdraji, MD<br>18 Porphyrin Metabolism Disorders<br>Maria Westerhoff, MD and Joseph Misdraji, MD<br>24 Dubin-Johnson Syndrome<br>Joseph Misdraji, MD and Sanjay Kakar, MD<br>26 Gilbert Disease<br>Joseph Misdraji, MD and Sanjay Kakar, MD<br>28 Progressive Familial Intrahepatic Cholestasis<br>Joseph Misdraji, MD<br>36 Cystic Fibrosis, Hepatic<br>Joseph Misdraji, MD<br>40 Hereditary Hemochromatosis<br>Joseph Misdraji, MD and Laura W. Lamps, MD<br>44 Wilson Disease<br>Joseph Misdraji, MD and Laura W. Lamps, MD<br>50 Alpha-1-Antitrypsin Deficiency<br>Nicole C. Panarelli, MD, Kari D. Caradine, MD, and Laura<br>W. Lamps, MD<br>54 Congenital Hepatic Fibrosis<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Hanlin L. Wang, MD, PhD<br>56 Polycystic Liver Disease<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Hanlin L. Wang, MD, PhD<br>58 Caroli Disease<br>Romil Saxena, MBBS, MD, FRCPath (UK)<br>  INFECTIOUS DISORDERS <br>60 Overview of Hepatitis<br>Nicole C. Panarelli, MD and Laura W. Lamps, MD<br>66 Acute Viral Hepatitis<br>Nicole C. Panarelli, MD and Lisa Yerian, MD<br>70 Hepatitis B<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>74 Hepatitis C<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>78 Hepatitis E<br>Maria Westerhoff, MD<br>82 Epstein-Barr Virus<br>Laura W. Lamps, MD, Maria Westerhoff, MD, and Hanlin<br>L. Wang, MD, PhD<br>86 Cytomegalovirus<br>Laura W. Lamps, MD<br>88 Herpes Simplex Virus<br>Sanjay Kakar, MD<br>90 Adenovirus<br>Maria Westerhoff, MD and Hanlin L. Wang, MD, PhD<br>92 Pyogenic Abscess<br>Laura W. Lamps, MD<br>96 Sepsis in Liver<br>Laura W. Lamps, MD<br>98 Mycobacterium tuberculosis<br>Laura W. Lamps, MD<br>102 Atypical Mycobacteria<br>Laura W. Lamps, MD<br>106 Cat-Scratch Disease<br>Laura W. Lamps, MD<br>108 Candidiasis<br>Laura W. Lamps, MD<br>110 Histoplasmosis<br>Joseph Misdraji, MD and Laura W. Lamps, MD<br>114 Cryptococcosis<br>Laura W. Lamps, MD<br>116 Amebiasis<br>Laura W. Lamps, MD<br>120 Schistosomiasis<br>Laura W. Lamps, MD<br>122 Echinococcosis<br>Laura W. Lamps, MD</p> <p>CHRONIC CHOLESTATIC AND AUTOIMMUNE DISORDERS<br>124 Autoimmune Hepatitis<br>Nicole C. Panarelli, MD and Lisa Yerian, MD<br>130 Primary Biliary Cholangitis<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>136 Primary Sclerosing Cholangitis<br>Hanlin L. Wang, MD, PhD<br>142 Ischemic Cholangitis<br>Maria Westerhoff, MD and Lisa Yerian, MD<br>144 Large Bile Duct Obstruction<br>Maria Westerhoff, MD and Laura W. Lamps, MD<br>148 Idiopathic Adulthood Ductopenia<br>Hanlin L. Wang, MD, PhD<br>PEDIATRIC CHOLESTATIC DISORDERS <br>150 Biliary Atresia<br>Romil Saxena, MBBS, MD, FRCPath (UK), Grace E. Kim, MD, and Matthew M. Yeh, MD, PhD<br>154 Idiopathic Neonatal Hepatitis<br>Romil Saxena, MBBS, MD, FRCPath (UK), Grace E. Kim, MD, and Matthew M. Yeh, MD, PhD<br>156 Syndromic Paucity of Intrahepatic Bile Ducts<br>(Alagille Syndrome)<br>Joseph Misdraji, MD, Romil Saxena, MBBS, MD, FRCPath (UK), and Matthew M. Yeh, MD, PhD<br>160 Nonsyndromic Paucity of Intrahepatic Bile Ducts<br>Romil Saxena, MBBS, MD, FRCPath (UK), Joseph Misdraji, MD, and Matthew M. Yeh, MD, PhD<br>  DRUG/TOXIN-RELATED HEPATITIS <br>164 Drug-Related Acute Hepatitis<br>Sanjay Kakar, MD<br>170 Drug-Induced Acute Hepatic Failure<br>Sanjay Kakar, MD<br>174 Drug-Induced Cholestatic Liver Injury<br>Sanjay Kakar, MD<br>176 Drug-Related Granulomatous Hepatitis<br>Laura W. Lamps, MD<br>180 Drug-Related Steatohepatitis/Phospholipidosis<br>Laura W. Lamps, MD<br>184 Reye Syndrome<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Lisa Yerian, MD<br>186 Drug-Related Cholangitis/Ductopenia<br>Maria Westerhoff, MD<br>192 Hepatic Stellate Cell Hyperplasia<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>  FATTY LIVER DISEASES <br>194 Alcoholic Liver Disease<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>200 Nonalcoholic Steatohepatitis<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>208 Glycogenic Hepatopathy<br>Maria Westerhoff, MD and Lisa Yerian, MD<br>210 Fatty Liver of Pregnancy<br>Nicole C. Panarelli, MD and Lisa Yerian, MD</p> <p>VASCULAR DISORDERS </p> <p>212 Portal Venous Obstruction<br>Hanlin L. Wang, MD, PhD<br>214 Hepatoportal Sclerosis<br>Hanlin L. Wang, MD, PhD<br>216 Hepatic Venous Outflow Obstruction<br>Sanjay Kakar, MD<br>220 Venoocclusive Disease<br>Sanjay Kakar, MD<br>222  Amyloidosis<br>Sanjay Kakar, MD<br>224 Ischemia<br> Rondell Graham, MBBS and Lisa Yerian, MD<br>226 Nodular Regenerative Hyperplasia<br>Sanjay Kakar, MD<br>  TRANSPLANTATION PATHOLOGY <br>228 Ischemia Reperfusion Injury<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Hanlin L. Wang, MD, PhD<br>230 Antibody-Mediated Rejection<br>Hanlin L. Wang, MD, PhD and Romil Saxena, MBBS, MD, FRCPath (UK)<br>232 T-Cell-Mediated Rejection (Acute Cellular Rejection)<br>Romil Saxena, MBBS, MD, FRCPath (UK)<br>236 Chronic Rejection<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Matthew M. Yeh, MD, PhD<br>238 Central Perivenulitis/Parenchymal Rejection<br>Rondell Graham, MBBS<br>240 Hepatic Artery Thrombosis<br>Rondell Graham, MBBS and Lisa Yerian, MD<br>242 Graft-vs.-Host Disease<br>Rondell Graham, MBBS and Lisa Yerian, MD<br>  TUMORS OF THE LIVER <br>244 Hepatic Adenoma<br>Sanjay Kakar, MD and Matthew M. Yeh, MD, PhD<br>252 Focal Nodular Hyperplasia<br>Sanjay Kakar, MD<br>256 Regenerative and Dysplastic Nodules<br>Sanjay Kakar, MD<br>262 Hepatocellular Carcinoma and Variants<br>Sanjay Kakar, MD<br>274 Fibrolamellar Carcinoma<br>Rondell Graham, MBBS<br>278 Combined Hepatocellular-Cholangiocarcinoma<br>Maria Westerhoff, MD<br>282 Hepatoblastoma<br>Rondell Graham, MBBS<br>286 Bile Duct Adenoma<br>Rondell Graham, MBBS and Sanjay Kakar, MD<br>288 von Meyenburg Complex (Biliary Microhamartoma) Sanjay Kakar, MD, Laura W. Lamps, MD, and Rondell Graham, MBBS<br>290 Mucinous Cystic Neoplasm, Liver<br>Maria Westerhoff, MD and Matthew M. Yeh, MD, PhD<br>294 Intrahepatic Cholangiocarcinoma<br>Rondell Graham, MBBS and Sanjay Kakar, MD<br>298 Intrahepatic Cholangiocarcinoma Histologic Subtypes<br>Rondell Graham, MBBS<br>302 Intraductal Papillary Neoplasm<br>Rondell Graham, MBBS<br>304 Hemangioma<br>Rondell Graham, MBBS<br>306 Angiomyolipoma<br>Rondell Graham, MBBS and Lisa Yerian, MD<br>310 Hepatic Small Vessel Neoplasm/Anastamosing Hemangioma<br>Maria Westerhoff, MD<br>314 Epithelioid Hemangioendothelioma<br>Sanjay Kakar, MD<br>316 Infantile Hemangioma<br>Sanjay Kakar, MD<br>318 Angiosarcoma<br>Sanjay Kakar, MD<br>320 Mesenchymal Hamartoma<br>Nicole C. Panarelli, MD, Hanlin L. Wang, MD, PhD, and Sanjay Kakar, MD<br>322 Embryonal Sarcoma<br>Nicole C. Panarelli, MD<br>324 Inflammatory Pseudotumor<br>Joseph Misdraji, MD<br>330 Segmental Atrophy (Nodular Elastosis)<br>Joseph Misdraji, MD<br>332 Hepatectomy Specimen Handling<br>Rondell Graham, MBBS and Laura W. Lamps, MD<br>  MISCELLANEOUS HEPATIC DISORDERS <br>334 Langerhans Cell Histiocytosis<br>Maria Westerhoff, MD and Hanlin L. Wang, MD, PhD<br>338 Hemophagocytic Syndromes<br>Hanlin L. Wang, MD, PhD</p> <p>  DEVELOPMENTAL/CONGENITAL <br>342 Congenital Pancreatic Cyst<br>Hanlin L. Wang, MD, PhD<br>344 Cystic Fibrosis, Pancreas<br>Hanlin L. Wang, MD, PhD<br>346 Nesidioblastosis<br>Hanlin L. Wang, MD, PhD<br>348 Choledochal Cyst<br>Romil Saxena, MBBS, MD, FRCPath (UK) and Laura W. Lamps, MD<br>350 Cholelithiasis<br>Laura W. Lamps, MD<br>352 Acute Cholecystitis<br>Sanjay Kakar, MD<br>354 Chronic Cholecystitis<br>Sanjay Kakar, MD<br>356 Xanthogranulomatous Cholecystitis<br>Laura W. Lamps, MD<br>358 Eosinophilic Cholecystitis<br>Laura W. Lamps, MD<br>360 Polyarteritis Nodosa and Other Vasculitides<br>Nicole C. Panarelli, MD<br>362 Parasitic Infection<br>Laura W. Lamps, MD</p> <p>NONNEOPLASTIC AND INFLAMMATORY DISORDERS OF THE PANCREAS</p> <p>366 Acute Pancreatitis<br>Grace E. Kim, MD and Alyssa M. Krasinskas, MD<br>368 Chronic Pancreatitis<br>Alyssa M. Krasinskas, MD and Lisa Yerian, MD<br>372 Autoimmune Pancreatitis<br>Alyssa M. Krasinskas, MD and Lisa Yerian, MD<br>376 Groove Pancreatitis<br>Alyssa M. Krasinskas, MD, Lisa Yerian, MD, and Vikram Deshpande, MD<br>378 Infectious Pancreatitis<br>Laura W. Lamps, MD<br>380 Pseudocysts<br>Alyssa M. Krasinskas, MD, Vikram Deshpande, MD, and Lisa Yerian, MD<br>382 Diabetes Mellitus<br>Laura W. Lamps, MD<br>384 Lymphoepithelial Cyst of the Pancreas<br>Alyssa M. Krasinskas, MD and Lisa Yerian, MD</p> <p>TUMORS OF THE GALLBLADDER AND EXTRAHEPATIC BILIARY TREE<br>386 Noninvasive Epithelial Polypoid Lesions</p> <p>390 Nicole C. Panarelli, MD and Sanjay Kakar, MD<br>Carcinoma of Gallbladder</p> <p>396 Nicole C. Panarelli, MD and Laura W. Lamps, MD<br>Carcinoma of Extrahepatic Bile Ducts</p> <p>402 Rondell Graham, MBBS and Laura W. Lamps, MD<br>Squamous/Adenosquamous Carcinoma, Gallbladder</p> <p>404 Hanlin L. Wang, MD, PhD<br>Neuroendocrine Neoplasms of Gallbladder</p> <p>408 Hanlin L. Wang, MD, PhD<br>Granular Cell Tumor</p> <p>410 Nicole C. Panarelli, MD<br>Embryonal Rhabdomyosarcoma</p> <p>412 Hanlin L. Wang, MD, PhD<br>Adenomyoma</p> <p>414 Nicole C. Panarelli, MD and Lisa Yerian, MD<br>Nonneoplastic Polypoid Gallbladder Lesions<br> Nicole C. Panarelli, MD and Laura W. Lamps, MD<br>  TUMORS OF THE PANCREAS <br>418 Pancreatic Intraepithelial Neoplasia<br>Alyssa M. Krasinskas, MD and Sanjay Kakar, MD<br>420 Ductal Adenocarcinoma, Including Variants Alyssa M. Krasinskas, MD, Sanjay Kakar, MD, and Mari Mino-Kenudson, MD<br>424 Undifferentiated Carcinoma<br>Wei Zheng, MD, Sanjay Kakar, MD, and Alyssa M. Krasinskas, MD<br>426 Adenosquamous Carcinoma, Pancreas<br>Alyssa M. Krasinskas, MD<br>428 Serous Cystadenoma<br>Sanjay Kakar, MD and Grace E. Kim, MD<br>432 Acinar Cell Cystadenoma<br>Maria Westerhoff, MD<br> </p> <p>436 Simple Mucinous Cyst<br>Maria Westerhoff, MD<br>438 Mucinous Cystic Neoplasm, Pancreas<br>Maria Westerhoff, MD<br>442 Intraductal Papillary Mucinous Neoplasm<br>Mari Mino-Kenudson, MD, Zaid Mahdi, MD, and Alyssa M. Krasinskas, MD<br>448 Intraductal Oncocytic Papillary Neoplasm<br>Alyssa M. Krasinskas, MD and Mari Mino-Kenudson, MD<br>450 Intraductal Tubulopapillary Neoplasm<br>Alyssa M. Krasinskas, MD and Mari Mino-Kenudson, MD<br>452 Acinar Cell Carcinoma<br>Laura W. Lamps, MD, Wei Zheng, MD, and Alyssa M. Krasinskas, MD<br>456 Pancreatoblastoma<br>Alyssa M. Krasinskas, MD, Laura W. Lamps, MD, and Matthew M. Yeh, MD, PhD<br>458 Dermoid Cyst<br>Zaid Mahdi, MD, Vikram Deshpande, MD, and Alyssa M. Krasinskas, MD<br>460 Poorly Differentiated Neuroendocrine Carcinoma,<br>Pancreas<br>Sanjay Kakar, MD<br>464 Well-Differentiated Neuroendocrine Tumor, Pancreas<br>Sanjay Kakar, MD<br>470 Solid-Pseudopapillary Tumors<br>Sanjay Kakar, MD<br>  TUMORS OF THE AMPULLA <br>474 Ampullary Adenoma<br>Hanlin L. Wang, MD, PhD<br>476 Ampullary Adenocarcinoma and Variants<br>Hanlin L. Wang, MD, PhD<br>480 Well-Differentiated Neuroendocrine Tumor, Ampulla<br>Hanlin L. Wang, MD, PhD<br>482 Gangliocytic Paraganglioma<br>Maria Westerhoff, MD<br>  SPECIMEN HANDLING, WHIPPLE <br>484 Specimen Handling, Whipple<br>Alyssa M. Krasinskas, MD and Laura W. Lamps, MD</p> <p> <br></p>

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        Diagnostic Pathology : Hepatobiliary and Pancreas