<p>Part 1. Cholesterol Chemistry and Cell Function</p> <p>1. Cholesterol chemistry, and laboratory synthesis<br>Hélio M.T. Albuquerque, Clementina M.M. Santos, and Artur M.S. Silva</p> <p>2. Molecular evolution of cholesterol and other higher sterols in relation to membrane structure<br>Ole G. Mouritsen</p> <p>3. Role of cholesterol in maintaining the physical properties of the plasma membrane<br>Witold K. Subczynski, Marta Pasenkiewicz-Gierula, Justyna Widomska, and Natalia Stein</p> <p>4. The fundamental interaction of cholesterol with lipid membranes: The umbrella model<br>Juyang Huang</p> <p>5. Model peptides and cholesterol<br>István P. Sugár and Parkson Lee-Gau Chong</p> <p>6. Cholesterol and ceramide: An unlikely pair<br>Aritz B. García-Arribas, Alicia Alonso, and Félix M. Goñi</p> <p>7. Cholesterol-recognizing amino acid consensus motifs in transmembrane proteins: Comparative analysis of in silico studies and structural data<br>Fodil Azzaz, Henri Chahinian, Nouara Yahi, Coralie Di Scala, Carlos J. Baier, Francisco J. Barrantes, and Jacques Fantini</p> <p>8. Effects of cholesterol on the GPCR AT1 receptor and its interplay with AT1 antagonists<br>S. Kiriakidi, Z. Cournia, and T. Mavromoustakos</p> <p>9. Principles of cholesterol regulation of ion channels<br>Qiu-Xing Jiang and Irena Levitan</p> <p>10. Fluorescent probes for microscopy visualization of cholesterol topography and dynamics in membranes<br>Francisco J. Barrantes</p> <p>11. Cholesterol transport in blood, lipoproteins, and cholesterol metabolism<br>Mark T Mc Auley and Amy E Morgan</p> <p>12. Common laboratory research methods for detection and quantification of cholesterol<br>Anna N. Bukiya, Hanxuan Li, Steven Mysiewicz, and Wei Li</p> <p>Part 2. Cholesterol Homeostasis and its disruption</p> <p>14. Diet-induced hypercholesterolemia in small laboratory animal models<br>Tina Herfel</p> <p>15. Nutrition and cholesterol metabolism<br>Ghada A. Soliman</p> <p>16. Cholesterol and early development<br>Isabella Ellinger and Waranya Chatuphonprasert</p> <p>17. Clinical and biochemical diagnostic methods: What do blood lipid levels tell us?<br>Marshall B. Elam</p> <p>18. Familial hypobetalipoproteinemia and abetalipoproteinemia<br>Francine K. Welty</p> <p>19. Critical illness and cholesterol levels<br>Zdenek Zadak</p> <p>20. Familial hypercholesterolemia<br>Shifa Jebari-Benslaiman, Unai Galicia-Garcia, Asier Larrea-Sebal, Kepa B. Uribe, Cesar Martin, and Asier Benito-Vicente</p> <p>21. Niemann-Pic type C disease (NPC)<br>Agnieszka Ługowska</p> <p>22. Rare monogenic disorders of cholesterol metabolism<br>Malgorzata Bednarska-Makaruk and Agnieszka Ługowska</p> <p>23. Secondary (acquired) hypercholesterolemia<br>Arrigo F.G. Cicero and Ivan R. Cincione</p> <p>24. Blood lipids and molecular pathways of atherogenesis<br>Ricardo Stein, Filipe Ferrari, and Vítor M. Martins</p> <p>25. Lysosomal acid lipase: Roles in rare deficiency diseases, myeloid cell biology, innate immunity, and common neutral lipid diseases<br>Gregory A. Grabowski and Hong Du</p> <p>26. Cholesterol and pathogens<br>Tatiana M. Clemente and Stacey D. Gilk</p> <p>27. Involvement of cholesterol and ß-amyloid in the initiation and progression of Alzheimer’s disease<br>Luis G. Aguayo, Jorge P. Roa, Carlos F. Burgos, and Juliana Gonzalez-Sanmiguel</p> <p>28. Cholesterol and alcohol<br>Andrew S. Bell, Emma M. O’Connell, and Falk W. Lohoff</p> <p>Part 3. Pharmacological Considerations and Perspectives</p> <p>29. Cholesterol stiffening of lipid membranes and drug interactions: Insights from neutron spin echo and deuterium NMR spectroscopy<br>Sudipta Gupta, Fathima T. Doole, Teshani Kumarage, Milka Doktorova, George Khelashvili, Rana Ashkar, and Michael F. Brown</p> <p>30. Cholesterol in drug delivery systems<br>DanRong Hu and ZhiYong Qian</p> <p>31. Modification of vascular receptor pharmacology by cholesterol: From molecular determinants to impact on arterial function<br>Alex M. Dopico, Anna N. Bukiya, and Kelsey C. North</p> <p>32. Clinical strategies for reducing cholesterol levels<br>Claude K. Lardinois and Samantha Karr</p> <p>33. Medicinal chemistry and pharmacology of statins<br>Bob M. Moore, II and George A. Cook</p> <p>34. Cyclodextrins as promising therapeutics against cholesterol overload <br>Florina Zakany, Tamas Kovacs, Lajos Szente, and Zoltan Varga</p> <p>35. Hyperlipidemia and rheumatoid arthritis<br>Aliki I. Venetsanopoulou, Paraskevi V. Voulgari, and Alexandros A. Drosos</p> <p>36. Management of hypercholesterolemia in individuals living with HIV/AIDS<br>Musaab Ahmed, Marium Ahmed, Dushyant Mital, and Mohamed H Ahmed</p>
