Polymeric Micelles for Drug Delivery
Paperback Engels 2022 9780323898683Samenvatting
Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles.
Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles – such as mucosal and transdermal – and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation.
Specificaties
Lezersrecensies
Inhoudsopgave
1. Polymeric micelles: pre´ cis for past, present, and future
2. Various polymers in the development of polymeric micelles
3. Solubility enhancement and drug release mechanism of polymeric micelles
4. Polymeric micellar nanomedicine for enhanced permeability and retention effect
5. Polymeric micelles for oral drug delivery
6. Polymeric micellar nanocarriers: topical treatment of inflammatory diseases
Part B: Application of polymeric micelles in drug delivery
7. Polymeric micelles in dermal and transdermal drug delivery
8. Polymeric micelles as delivery systems for anticancer immunotherapy
9. Polymeric micelles for drug delivery in oncology
10. Surface engineering of polymeric micelles for imparting multifunctionality
11. Cellular interaction of polymeric micelles in targeted drug delivery systems: the road from tissue to cell
Part C: Stimuli-responsive polymeric micelles for drug delivery
12. pH-responsive polymeric micelles for drug delivery
13. Enzyme-responsive polymeric micelles for drug delivery applications
14. Light- and temperature-responsive polymeric micelles for drug delivery
15. Exogenous stimuli
16. Dual-responsive polymeric micelles for drug delivery
Part D: Recent advances in polymeric micelles
17. Polymeric micelles for drug codelivery
18. Nose-to-brain delivery
19. The application of a drug
20. Polymeric micelles with cleavable links for drug delivery
21. Block copolymer micelles as long-circulating drug delivery vehicles
22. Triblock polymeric micelles as an emerging nanocarrier for drug delivery
Part E: Environmental and regulatory aspects
23. Biological toxicity and environmental hazards associated with polymeric micelles
24. Clinical translation of polymeric micelles into market
25. Regulatory pathways and prospects for polymeric micelles
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