, ,

Glycolysis

Tissue-Specific Metabolic Regulation in Physio-pathological Conditions

Paperback Engels 2023 9780323917049
€ 187,00
Levertijd ongeveer 9 werkdagen
Gratis verzonden

Samenvatting

Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research.

Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis.

Specificaties

ISBN13:9780323917049
Taal:Engels
Bindwijze:Paperback

Lezersrecensies

Wees de eerste die een lezersrecensie schrijft!

Inhoudsopgave

PART I GLYCOLYSIS AND PHYSIOLOGICAL PROCESSES<br>1. Development and glycolysis dependence<br>2. Neuro-glia communication and glycolysis<br>3. Glycolysis and skeletal muscle plasticity<br>4. Glycolysis and trained heart<br>5. Bone glycolysis and the regulation of energy balance<br>6. Glycolysis in adipose tissue-dependent thermogenesis<br>7. Regulation of glycolysis from a liver-centric perspective <br>8. Glycolysis as a rheostat mechanism in pancreas function<br>9. The Warburg-like effect in reproductive events<br><br>PART II GLYCOLYSIS AND PATHOLOGICAL EVENTS <br>10. Exploring glycolytic adaptations in cancer cells<br>11. The glycolytic pathway to heart failure<br>12. Glycolysis in PAH and COPD metabolic reprogramming<br>13. Glycolysis and mitochondrial function in diabetes mellitus <br>14. Metabolic adaptation to glycolysis as a basic defense mechanism of immune cells<br>15. Inborn glycolytic pathway defects<br>16. Enhanced glycolysis and metabolic complications of hematologic malignancies<br>17. Implications of glycolysis for osteoporosis pathogenesis<br>18. Glucose, glycolysis, and neurodegenerative diseases<br>19. Viral Infections and glycolysis<br><br>SUPPLEMENTAL INFORMATION – Methodological approaches<br>20. The application of Omics to explore glycolysis <br>21. An interactive analysis of glycolysis regulation<br>22. Measuring glycolysis flux

Managementboek Top 100

€ 187,00
Levertijd ongeveer 9 werkdagen
Gratis verzonden

Rubrieken

    Personen

      Trefwoorden

        Glycolysis