PART I: Clinical Evaluation <br>1. General Aspects of the Patient’s Neurologic History<br>2. Neurologic Examination of the Older Child<br>3. Neurologic Examination of Young Children (Ages 1–5 Years)<br>4. Neurologic Examination of Infants (Ages 0–1 Year)<br>5. Motor Signs<br>6. Vision Loss<br>7. Hearing Impairment<br>8. Vertigo<br>9. Taste and Smell<br>10. Neuropsychological Assessment<br><br>PART II: Care of the Child With Neurologic Disorders <br>11. Counseling Children With Neurologic Disorders and Their Families<br>12. Pediatric Neurorehabilitation Medicine<br>13. Pediatric Palliative Care, Pain, and Symptom Management<br>14. Practical Bioethics in Child Neurology<br>15. Transitional Care for Children With Neurologic Disorders<br>16. Practice Guidelines in Pediatric Neurology<br>17. Measurement of Health Outcomes in Pediatric Neurologic Disorders<br>18. Computer Resources, Artificial Intelligence, and Telemedicine<br>19. Education and Training of Child Neurologists and Workforce Issues<br><br>PART III: Neurodiagnostic Testing <br>20. Cerebrospinal Fluid Examination<br>21. Pediatric Neuroimaging<br>22. Pediatric Neurophysiologic Evaluation<br><br>PART IV: Global Child Neurology <br>23. Regional and Global Implications for Children’s Brain Health<br>24. Implementing Child Neurology Care in Resource-Limited Settings<br>25. Adaptation and Implementation of Guidelines at the Local Level<br><br>PART V: Neonatal Neurology <br>26. Neonatal Neuro-Intensive Care<br>27. Provoked Neonatal Seizures and Neonatal Onset Epilepsy<br>28. Hypoxic-Ischemic Brain Injury in the Term Newborn<br>29. Cerebrovascular Disorders in the Newborn<br>30. Neonatal Nervous System Trauma<br>31. Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury<br>32. Perinatal Metabolic Encephalopathies<br><br>PART VI: Environment and Brain Development <br>33. The Neural Exposome and Environmental Neuroscience<br>34. Adverse Childhood Experiences<br>35. The Neurological Impact of Prenatal Substance Exposure<br>36. Environmental Pollutants<br>37. Malnutrition, Nutrition, and Dietary Toxins<br>38. Poisoning and Drug-Induced Neurologic Diseases<br><br>PART VII: Congenital Structural Defects <br>39. Introduction to Human Brain Malformations<br>40. Disorders of Neural Tube Development<br>41. Disorders of Forebrain Development<br>42. Disorders of Cerebellar and Brainstem Development<br>43. Microcephaly and Megalencephaly: Disorders of Brain Size<br>44. Malformations of Cortical Development<br>45. Hydrocephalus, Cysts, and Cystic Malformations<br>46. Congenital Anomalies of the Skull<br>47. Prenatal Diagnosis of Structural Brain Anomalies<br><br>PART VIII: Neurogenetics <br>48. Neurogenetics in the Genome Era<br>49. Genetic Counseling in the Genomic Era<br>50. Chromosomes and Chromosomal Abnormalities<br>51. Single-Gene Abnormalities<br>52. Neurocutaneous Disorders<br>53. Emerging Gene-Based Pathways: Channelopathies (Epilepsy and Beyond)<br>54. Emerging Gene-Based Pathways: mTORopathies<br>55. Emerging Gene-Based Pathways: RASopathies<br>56. Emerging Gene-Based Pathways: Chromatin Remodeling Disorders<br>57. The Neuronal Ceroid Lipofuscinoses<br><br>PART IX: Metabolic Disorders <br>58. Approach to the Patient With a Metabolic Disorder<br>59. Aminoacidemias and Organic Acidemias<br>60. Urea Cycle Disorders<br>61. Diseases Associated With Primary Abnormalities in Carbohydrate Metabolism<br>62. Disorders of Glycosylation<br>63. Lysosomal Storage Diseases<br>64. Mitochondrial Diseases<br>65. Peroxisomal Disorders<br>66. Neurotransmitter-Related Disorders<br>67. Disorders of Vitamin Metabolism<br><br>PART X: Neurodevelopmental Disorders <br>68. Neurodevelopmental Disabilities: Conceptual Framework<br>69. Intellectual Developmental Disorder and Global Developmental Delay<br>70. Regressive and Degenerative Genetic Neurological Disorders<br>71. Developmental Encephalopathies<br>72. Developmental Language Disorders<br>73. Nonverbal Learning Disorders<br>74. Dyslexia<br>75. Attention-Deficit/Hyperactivity Disorder<br>76. Autism Spectrum Disorder<br>77. Cerebral Palsy<br>78. Developmental Coordination Disorder<br>79. Treatment of Neurodevelopmental Disorders<br>80. Neuropsychopharmacology<br><br>PART XI: Epilepsy <br>81. Overview of Seizures and Epilepsy in Children<br>82. Principles of Management and Outcome<br>83. Pathophysiology of Seizures and Epilepsy<br>84. Epilepsy Genetics<br>85. Febrile Seizures<br>86. Generalized Seizures<br>87. Focal and Multifocal Seizures<br>88. Myoclonic Seizures<br>89. Infantile Epileptic Spasms Syndrome<br>90. Status Epilepticus<br>91. Electroclinical Syndromes: Neonatal Onset<br>92. Electroclinical Syndromes: Infantile Onset<br>93. Electroclinical Syndromes: Childhood Onset<br>94. Electroclinical Syndromes: Adolescent Onset<br>95. Focal Structural Epilepsy<br>96. Acquired Epilepsies: Trauma, Stroke, and Tumors<br>97. Inherited Metabolic Epilepsies<br>98. Antiseizure Medication Therapy in Children<br>99. Epilepsy Surgery in the Pediatric Population<br>100. Neuromodulation in Epilepsy<br>101. Ketogenic Diets<br>102. Behavioral, Cognitive, and Social Implications of Childhood Epilepsy<br>103. Mortality in Children With Epilepsy<br><br>PART XII: Nonepileptiform Paroxysmal Disorders <br>104. Headache in Children and Adolescents<br>105. Breath-Holding Spells and Reflex Anoxic Seizures<br>106. Psychogenic Nonepileptic Seizures and Psychiatric Disorders<br>107. Functional Neurological Symptom Disorder in Children and Adolescents<br>108. Syncope and Postural Orthostatic Tachycardia Syndrome<br>109. Brief Resolved Unexplained Events, Apparent Life-Threatening Events, and Sudden Infant Death Syndrome<br><br>PART XIII: Disorders of Sleep <br>110. Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents<br>111. Nocturnal Paroxysmal Disorders<br>112. Disorders of Excessive Sleepiness<br><br>PART XIV: Disorders of Balance and Movement <br>113. The Cerebellum and the Hereditary Ataxias<br>114. Movement Disorders: An Overview<br>115. Paroxysmal Dyskinesias<br>116. Movement Disorders of Infancy<br>117. Drug-Induced Movement Disorders in Children<br>118. Tics and Tourette Syndrome<br><br>PART XV: White Matter Disorders <br>119. Genetic and Metabolic Disorders of the White Matter<br>120. Acquired Disorders Affecting the White Matter<br><br>PART XVI: Brain Injury and Disorders of Consciousness <br>121. Impairment of Consciousness and Coma<br>122. Traumatic Brain Injury in Children<br>123. Abusive Head Trauma<br>124. Hypoxic-Ischemic Encephalopathy in Infants and Older Children<br>125. Disorders of Intracranial Pressure<br>126. Spinal Cord Injury<br>127. Determination of Brain Death/Death by Neurologic Criteria in Infants and Children<br><br>PART XVII: Cerebrovascular Disease in Children <br>128. Arterial Ischemic Stroke in Infants and Children<br>129. Sinovenous Thrombosis<br>130. Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children<br>131. Cerebral Arteriopathies<br>132. Coagulation Disorders and Cerebrovascular Disease in Children<br><br>PART XVIII: Infections of the Nervous System <br>133. Bacterial Infections of the Nervous System<br>134. Viral Infections of the Nervous System<br>135. Fungal, Rickettsial, and Parasitic Diseases of the Nervous System<br>136. Neurologic Complications of Immunization<br><br>PART XIX: Immune-Mediated Disorders of the Nervous System <br>137. Diagnosis and Management of Pediatric Neuroimmunological Disorders<br>138. Autoimmune Encephalitis<br>139. Autoimmune-Associated Epilepsies<br>140. Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus, and Pediatric Acute Neuropsychiatric Syndrome<br>141. Immune-Mediated Cerebellar Disorders<br>142. Neurorheumatology<br><br>PART XX: Pediatric Neuro-Oncology <br>143. Pediatric Neuro-Oncology: An Overview<br>144. Medulloblastoma<br>145. Other Embryonal and Pineal Malignancies of the Central Nervous System<br>146. Ependymoma<br>147. Pediatric-Type Diffuse High-Grade Glioma<br>148. Pediatric Low-Grade Glioma<br>149. Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma<br>150. Atypical Teratoid/Rhabdoid Tumors<br>151. Central Nervous System Germ Cell Tumors<br>152. Craniopharyngiomas, Meningiomas, and Schwannomas<br>153. Pediatric Intradural Spinal Cord Tumors<br>154. Systemic Cancers and Central Nervous System Involvement<br>155. Treatment-Related Neurologic Sequelae of Pediatric Central Nervous System Tumors<br><br>PART XXI: Neuromuscular Disorders<br>156. Muscle and Nerve Development in Health and Disease<br>157. Diagnostic Testing in Children With Suspected Neuromuscular Disorders<br>158. Clinical Assessment of Pediatric Neuromuscular Disorders<br>159. The Floppy Infant<br>160. Classic Proximal Spinal Muscular Atrophy<br>161. Other Motor Neuron Diseases of Childhood<br>162. Genetic Peripheral Neuropathies<br>163. Acquired Peripheral Neuropathies<br>164. Inflammatory Neuropathies<br>165. Congenital Myasthenic Syndromes<br>166. Acquired Disorders of the Neuromuscular Junction<br>167. Duchenne and Becker Muscular Dystrophy<br>168. Congenital, Limb-Girdle, and Other Muscular Dystrophies<br>169. Congenital Myopathies<br>170. Metabolic Myopathies<br>171. Inflammatory Myopathies<br>172. Channelopathies: Myotonic Disorders and Periodic Paralysis<br>173. Multidisciplinary Management of Children With Neuromuscular Conditions<br><br>PART XXII: Systemic and Autonomic Nervous System Diseases<br>174. Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence<br>175. Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice<br>176. Disorders of Micturition and Defecation<br>177. Neurologic Disorders in Children With Heart Disease<br>178. Neurologic Disorders Associated With Renal Diseases<br>179. Neurologic Manifestations and Disorders Associated With Gastrointestinal Diseases<br><br>Index