Wael Mohamed
Translational Models of Parkinson’s Disease and related Movement Disorders
Paperback Engels 2024 9780443161285
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.
Specificaties
Lezersrecensies
Wees de eerste die een lezersrecensie schrijft!
Inhoudsopgave
<p>Section I. Understanding PD and related movement disorders<br>1. Neuroinflammation, glymphatic system, and Parkinson's disease<br>2. Pharmacotherapy of PD and related movements disorders and their limitations<br>3. Diagnosis and biomarkers of Parkinson's disease and related movement disorders<br>4. OMICS and bioinformatics in Parkinson disease and related movements disorders<br>5. Modeling Parkinson's disease with the alpha-synuclein protein<br>6. α-Synuclein seeding assay and analysis<br>Section II. Mammalian models of Parkinson's disease<br>7. SHH, nurr1, pitx3, and en1 models for Parkinson's disease<br>8. Stem cell for PD: Technical considerations<br>9. Deep brain stimulation using animal models of Parkinson's disease<br>10. The MitoPark mouse model of Parkinson's disease<br>11. The beta-sitosterol beta-D-glucoside (BSSG) rat model of Parkinson's disease<br>Section III. Invertebrate models of Parkinson's disease<br>12. SCA1 zebrafish model<br>13. Various zebrafish models of Parkinson's disease: What gives us hope<br>14. Drosophila PD model<br>15. Caenorhabditis elegans models of tauopathy<br>16. LRRK2 in Caenorhabditis elegans model<br>Section IV. Ethics and regulations related to translational PD models<br>17. Confounding factors for validation of PD models<br>18. Neurobehavioral characterization of PD models<br>19. Ethical regulations for induction and validation of PD models<br>20. The OMICS and PD models: Hopes or hypes<br>21. Parkinson's disease from an Ayurveda perspective: Opportunities and challenges for further research</p>
Rubrieken
- advisering
- algemeen management
- coaching en trainen
- communicatie en media
- economie
- financieel management
- inkoop en logistiek
- internet en social media
- it-management / ict
- juridisch
- leiderschap
- marketing
- mens en maatschappij
- non-profit
- ondernemen
- organisatiekunde
- personal finance
- personeelsmanagement
- persoonlijke effectiviteit
- projectmanagement
- psychologie
- reclame en verkoop
- strategisch management
- verandermanagement
- werk en loopbaan