Steroid Biochemistry

<p>Section I. Cytochrome P450 Enzymes <br>1. Steroidogenic P450s (CYP11A1, 17A1, 21A2, 11B1, and 11B5)<br>Emily Scott<br>2. Steroid 17alpha-hydroxylase/17,20-lyase (Cytochrome P450 17A1)<br>F. Peter Guengerich, Yasuhiro Tateishi, Kevin D. McCarty and Lu Liu</p> <p>Section 2. Enzymes of Estrogen Biosynthesis <br>3. Aromatase and Steroid Sulfatase<br>Debashi Ghosh<br>4. Estrogenic 17b-Hydroxysteroid Dehydrogenase</p> <p>Section 3. Hydroxysteroid Dehydrogenases (HSD) <br>5. 3a-Hydroxyssteroid Dehydrogenase(s)<br>6. Approaches to Measuring 3b-Hydroxysteroid Dehydrogenase Type 1<br>Nima Sharifi<br>7. 3b-Hydroxysteroid Dehydrogenase Type 2<br>8. 11b-Hydroxysteroids Dehydrogenase Type 1<br>Alex Odermatt<br>9. 11b-Hydroxysteroids Dehydrogenase Type 2<br>Alex Odermatt<br>10. 17b-Hydroxysteroid Dehydrogenases<br>Tea Lanisnik Rizner</p> <p>Section 4. Steroid Reductases <br>11. Approaches for evolutionary, biochemical, and structural analysis of bacterial steroid 5a-reductases<br>Ren Ruobing<br>12. Mammalian Steroid 5a-Reductase<br>Richard J. Auchus<br>13. Human Steroid 5b-Reductase (AKR1D1)<br>Trevor Martin Penning<br>14. Human Aldo-Keto Reductases (AKR1C1-AKR1C4)-Cloning & Expression of Recombinant Enzymes<br>Trevor Martin Penning and Andrea Detlefsen</p> <p>Section 5. Steroid Conjugating Enzymes <br>15. Steroid sulfotransferases-X SULT2A1, 2B1b and 1E1<br>Charles Napoleon Falany<br>16. Steroid UGT-Glucuronsyl Transfereases</p> <p>Section 6. Steroid Analytical Chemistry <br>17. Mass spectrometry of Glucocorticiids<br>18. Mass spectrometry of Progestins<br>19. LC-MS Quantitation of Hydroxy- and Keto-Androgens<br>Clementina Mesaros, Andrea Detlefsen and Ryan Paulukinas<br>20. Quantification of 11-oxygenated androgens by RP-UV-HPLC post 2,4-dinitrophenylhydrazine derivatization<br>Ryan Paulukinas<br>21. 11-Oxygenated Androgens<br>Amanda Swart<br>22. LC-MS Quantitation of Estrogens<br>Clementina Mesaros</p>