Adenosine A2A Receptor Antagonists

<p>1. A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonists<br>Kenneth A. Jacobson<br>2. Chemistry – agonists, antagonists, partial agonists, inverse agonists<br>Christa Müller<br>3. Functional roles of adenosine receptors – biochemistry and neuronal plasticity<br>Ana Sebastiao<br>4. A2A and Depression <br>Rodrigo Cunha<br>5. A2AR and glial function<br>Zhihua Gao<br>6. The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signalling <br>Rafael Franco, Gemma Navarro and Eva Martinez-Pinilla<br>7. How and why A2a receptor become to be a therapeutic target in Parkinson’s disease therapy<br>Peter Jenner<br>8. Development of A2a antagonists for Parkinson’s disease – clinical evaluation for motor and non-motor symptoms<br>Yasar Torres-Yaghi<br>9. The role of A2AR in chemobrain and the potential therapeutic benefits of istradefylline<br>Detlev Boison and Mi-hyeon Jang<br>10. Effects of adenosine A2A receptors on cognitive function in health and disease<br>Anna G. Orr, Cinthia Garcia and Avital Licht-Murava<br>11. A2a receptor and Sleep disturbance <br>Michael Lazarus and Mustafa Korkutata<br>12. Adenosine A2A signals and Dystonia<br>Makio Takahashi<br>13. Protective potential of caffeine and adenosine A2A adenosine receptor antagonism in LRRK2 Parkinson’s disease<br>Michael Schwarzschild<br>14. A2a antagonists and Alzheimer’s disease<br>David Blum<br>15. A2a receptors and ALS/MS<br>Zheng Wu<br>16. A2AR and trauma/PTSD<br>Yuanguo Zhou</p>