Substance P

From Pain to Cancer

Paperback Engels 2024 9780443221941
€ 225,39
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Samenvatting

Substance P: From Pain to Cancer, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, provides a complete discussion of substance P biology, its role in normal physiology and a variety of diseases.

The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.

Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.

Specificaties

ISBN13:9780443221941
Taal:Engels
Bindwijze:Paperback

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Inhoudsopgave

<p>1. The synthesis, release, and binding of substance P<br>Brendan A. Hilliard, Robert Vink, and Mary F. Barbe<br>2. Distribution of substance P receptors in mammals<br>Honoo Satake, Akira Shiraishi, and Tsuyoshi Kawada<br>3. Substance P in nonmammalian biology: Evolutionarily conserved tachykinin signaling<br>Dick R. Nassel<br>4. Methodological foundations of substance P detection<br>Nuray Erin<br>5. Substance P receptor antagonists<br>Francisco D. Rodrıguez and Rafael Covenas<br>6. Substance P in the cardiovascular system<br>Magdalena Chottova Dvorakova and Shashank Pandey<br>7. Substance P in lower urinary tract function and dysfunction<br>Mitsuharu Yoshiyama<br>8. Role of the substance P in learning and memory<br>Natalia Favila and Paul G. Overton<br>9. Substance P in nausea and vomiting<br>Paul L.R. Andrews, John A. Rudd, and Gareth J. Sanger<br>10. Substance P in the central control of respiration<br>Nicholas J. Burgraff and Jan-Marino Ramirez<br>11. Substance P in bone metabolism<br>Tanja Niedermair and Susanne Grassel<br>12. Life without substance P: The naked mole rat<br>Aishi Zhao, Jiwon Lee, Weronika Gryszkiewicz, and Thomas J. Park<br>13. Substance P in inflammation<br>Sophie E. Sipprell and Ian Marriott<br>14. Substance P in oxidative stress<br>Seyed Isaac Hashemy and Safieh Ebrahimi<br>15. Substance P in pain<br>Robert Vink<br>16. Substance P in cancer<br>Miguel Munoz, Marisa Rosso, Riffat Mehboob, and Francisco Esteban<br>17. Substance P in cardiac dysfunction<br>Scott P. Levick and Alexander Widiapradja<br>18. Substance P in neurotrauma<br>Rebecca George, Justin Krieg, and Frances Corrigan<br>19. Substance P in stroke<br>Annabel Sorby-Adams<br>20. Substance P in Alzheimer&rsquo;s and Parkinson&rsquo;s disease<br>Severini Cinzia<br>21. Substance P receptor antagonists for major depressive disorder<br>Nadia M.J. Rupniak and Mark S. Kramer<br>22 From a putative antidepressant to a validated mouse model of ADHD via NK1 receptors<br>S.C. Stanford<br>23. Substance P in stress and anxiety<br>Karl Ebner and Nicolas Singewald<br>24. Substance P-neurokinin 1 receptor pathway in musculoskeletal disorders<br>Brendan A. Hilliard and Mary F. Barbe<br>25. Substance P and sudden infant death syndrome (SIDS)<br>F. Bright, Robert Vink, and R.W. Byard<br>26. Immunobiology and pharmacology of neuropeptide substance P<br>Ehsan Aslam, Asina Gijasi, Caroline Perner, Rob van Wijk, Anne-Grete Martson, Gerard J.P. van Westen, Ilze Bot, Laura H. Heitman, and Alireza Mashaghi<br>27. Substance P in viral diseases—Especially coronavirus disease<br>Riffat Mehboob, Mariam Hashim, and Miguel Munoz<br>28. Substance P: Perspectives and future directions<br>Robert Vink<br> </p>

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