Artificial Metalloproteins

1. Incorporating Non-Native Cofactors into Heme Proteins<br>Christopher Lemon<br>2. Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-like Cofactors<br>Samuel Mann<br>3. Cobalt-Substituted Hemoprotein Expression<br>Andrew Buller<br>4. Rationally designed directed evolution of cytochrome P450 enzymes<br>Shyamalava Mazumdar<br>5. De novo design of a switchable ??-helical hemoprotein<br>Vincent Louis Pecoraro<br>Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme<br>6. Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes<br>Woon Ju Song<br>7. Development of a PQQ-Dependent Artificial Metalloprotein<br>Lisa Olshansky<br>8. Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme<br>Akira Onoda<br>9. Design and Application of Nonheme Iron Enzymes<br>Xiongyi Huang<br>Part C: Secondary Sphere Modulation for Metallocofactor Activation<br>10. Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds<br>Yi Lu<br>11. De Novo-Designed Artificial Cu Proteins and Electron Transfer<br>Saumen Chakraborty<br>12. Design and Evaluation of Biocatalysts for Energy-Related Reactions<br>Kara Bren<br>Part D. Superstructural Control: Tertiary and Quaternary Effects in Metalloprotein Design<br>13. Breaking Symmetry: Metal-Guided Assembly of Heterotrimeric Coiled Coils<br>Vincent Louis Pecoraro and Salvatore La Gatta<br>14. Engineering Conformationally Switchable Artificial Metalloproteins<br>Lisa Olshansky<br>15. Chemical Methods to Stabilize Segments of Metalloproteins in the Form of Peptides<br>Andy Nguyen<br>16. Design and Production of De Novo Protein Nanowires<br>Ross Anderson