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Chalcones

From Drug Discovery to Pharmaceutical Applications

Paperback Engels 2026 9780443438127
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Samenvatting

Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases.

Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

Specificaties

ISBN13:9780443438127
Taal:Engels
Bindwijze:Paperback

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Inhoudsopgave

Part I - Foundations of Chalcones research<br>1. Natural sources of Chalcones<br>2. Extraction methods from traditional to green approaches<br>3. Structural and spectroscopic characterization of Chalcones<br>4. Synthesis, structural modifications and scale-up methods<br>5. Medicinal Chemistry Strategies in the Chalcone scaffold<br>6. Chalcones as versatile intermediates in organic chemistry<br>7. Chalcones in metal complexes<br><br>Part II – Pharmacology of Chalcones<br>8. PK properties and bioavailability of Chalcones<br>9. Chalcone Toxicity<br>10. Natural Chalcones in Traditional Medicine<br>11. Chalcones as Antiviral Agents<br>12. Chalcones as Antibacterial and Antitubercular Agents<br>13. Anticancer Potential of Chalcones<br>14. Chalcones as Neuroprotective and Anti-Alzheimer&rsquo;s Disease Agents<br>15. Chalcones as Antiprotozoal, Antiparasitic and Insecticidal Agents<br>16. Chalcones as Antifungal Agents<br>17. Chalcones as Anti-inflammatory, Anti-ulcer and Antioxidant Agents<br>18. Chalcones as Anti-hyperlipidemic, Anti-diabetic and Insulin Regulating Agents<br><br>Part III – Prospects<br>19. Chalcone-containing Products (food supplements, nutraceuticals, functional food)<br>20. Formulations and Drug Delivery of Chalcones<br>21. Chalcone-protein co-crystals in the PDB<br>22. Clinical Trials of Chalcone-based drug candidates

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€ 224,19
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        Chalcones